Some middle-aged and elderly people are not unfamiliar with aspirin and statins. The former is not only an antipyretic and analgesic drug, but also can inhibit platelet aggregation, avoid thrombosis, and effectively prevent myocardial infarction and cerebral ischemia. ; The latter role is to reduce bad cholesterol and triglyceride levels, used to treat hyperlipidemia, stabilize atherosclerotic plaques, improve vascular endothelial function, and also prevent thrombosis. Aspirin and statins play an important role in preventing cardiovascular and cerebrovascular diseases, and what are the benefits of the two?
What are the benefits of long-term use of statin + aspirin?
1. Prevention and treatment of thrombus and plaque
Plaque and thrombus are the main causes of stenosis or blockage of blood vessels factor. As the blood changes, blood clots will reach blood vessels all over our body. Blocking cerebral arteries can lead to cerebral infarction, and blocking coronary arteries can lead to myocardial infarction.
Aspirin has an antithrombotic effect. Its mechanism is to avoid the phenomenon of platelet adhesion and accumulation, and it can also inhibit the release of platelets, thereby resisting thrombosis. Aspirin has a long half-life and can be used for one day. Just once.
Statins are not ordinary lipid-lowering drugs, they can directly act on plaques in blood vessels piece. Bad cholesterol is easily deposited in the vascular endothelium, and plaques are formed slowly. Statins can reduce the level of bad cholesterol and control the growth of plaques; the rupture of plaques in coronary vessels can induce acute coronary syndrome, and statins can reduce plaque Inflammatory factors in the block, reducing inflammatory cells, thereby stabilizing the plaque, preventing the formation of blood clots, and reducing the risk of cardiovascular disease.
Research shows that receiving intensive statin therapy may reverse atherosclerosis; statins also reduce tissue factor activity, control thrombin, and have anticoagulant and anticoagulant properties. Platelet efficacy, avoid thrombosis.
2. Extend the life of cardiac stents
Cardiac stenting should be done immediately when the blood vessel is narrowed more than 75% or the blood vessel is blocked. What worries patients the most is that the stent is blocked again, and the stent cannot be installed with a second operation, which increases the pain suffered by the patient. Taking statins combined with aspirin in strict accordance with the doctor’s instructions after stenting can prevent thrombosis and atherosclerosis, thereby maintaining the patency of the stent and prolonging the life of the stent.
3. Reducing cancer risk
Statins and aspirin are not only beneficial for Cardiovascular system, but also has anti-cancer properties.
The Lancet< span> Published research shows that taking aspirin in small doses every day, about 75-300 mg, can prevent the metastasis of various cancers and reduce the incidence of cancer.
Harvard UniversityThe research team has also done research and showed that taking such drugs in small doses, the daily dose is less than 100 mg may reduce the risk of ovarian cancer.
Annuals of OncologyA study shows that long-term use of aspirin may reduce Reduce the risk of gastrointestinal tumors, including colon cancer, liver cancer, etc. Studies have shown that mutations in the P53 gene are closely related to cancer, and statins can act on this gene signaling pathway, so they have anti-cancer effects.
Message from the doctor
It can be seen that these two This drug brings so many benefits. However, when you are in good health, you should not take the medicine at will, so as not to increase the burden on the liver and kidneys, and at the same time, it will also hurt the stomach.
Family doctor online feature, unauthorized reprint