▎WuXi Adapt Content Team Editor
Liver cancer, is one of the leading causes of human death. Poet Wang Guozhen, film and television actors Shen Dianxia, Fu Biao, Wu Mengda, singer Luo Wen… Many famous people died of liver cancer.
Even more worrying, liver cancer incidence and deaths are still increasing.
According to a study led by the World Health Organization’s International Agency for Research on Cancer (IARC) and published in the Journal of Hepatology, if people do not take further control of liver cancer Measures, including prevention, screening, etc. It is estimated that by 2040, the number of liver cancer incidence and deaths worldwide will increase by more than 55% compared with 2020, and nearly half of them will occur in China.
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Global Burden of Liver Cancer 2020
Study results show that in 2020, there will be 905,700 new cases of liver cancer worldwide, resulting in 830,200 deaths, which is the world’s the first 6 Large new cancer and 3 largest cause of cancer death.
China is a veritable liver cancer country, with 410,000 new liver cancer cases in 2020, resulting in 391,200 >personal deaths, accounting for 45.3% and 47.1% of new and 47.1% of global deaths, respectively, China’s number5 >The most common new cancer and the 2 leading cause of cancer death.
Global burden of liver cancer in 2024
Research predicts that if people do not take further prevention and control measures, the incidence and mortality of liver cancer will remain on the current trend, and it is expected that by 2040, the world will have a new 1.4 million cases of liver cancer, an increase of 55.0% over 2020; resulting in 1.3 million deaths, an increase of 56.4% over 2020< /strong>. And nearly 50% of the new and fatalities will still be in China.
In order to avoid the increase in the incidence and death of liver cancer, research suggests that countries around the world must adopt prevention and control measures, including primary prevention and screening of liver cancer, etc. Rates and mortality are reduced by at least 3% per year.
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Be aware of these risk factors
Studies show that although hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the most common cause of liver cancer However, in recent years, excessive drinking, metabolic syndrome, type 2 diabetes, obesity and nonalcoholic steatohepatitis have also become prominent causes of liver cancer.
In addition, other risk factors, such as smoking, consumption of aflatoxin-contaminated food, and liver fluke infection, also contribute to the development of liver cancer. .
Studies have shown that about 56% of new liver cancers worldwide are associated with HBV infection; 20% are associated with HCV infection ; 18% were related to smoking; 17% were related to drinking.
What about the future?
Research suggests that the incidence of liver cancer should be substantially reduced through primary prevention measures, such as HBV infection immunization, detection and treatment; HCV infection detection and treatment; reduce alcohol consumption; curb the rising prevalence of diabetes and obesity, etc. Specifically, the following aspects should be done.
1. Prevention of HBV and HCV infection
Timely vaccinate against hepatitis B, and do not have unprotected sex with people infected with HBV (if one of the couples is infected, liver function should be assessed in advance when trying to conceive, and the Pregnancy preparation; at the same time, regular obstetric examinations and hepatitis B blockade); Do not use illegal drugs, do not share needles; be cautious when puncturing and tattooing, use sterile needles; vaccinate in advance when going to areas with high hepatitis B incidence Vaccines.
At the same time, use injections safely and appropriately; avoid going to informal medical institutions; avoid illegal ways to donate and collect blood; and prevent contact with blood during sexual intercourse.
For HBV or HCV-infected individuals, standardized antiviral treatment and monitoring as prescribed should be followed.
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2. Don’t eat moldy food
Aflatoxins are a class of toxins produced by Aspergillus flavus and Aspergillus parasiticus. They are class 1 carcinogens and are mainly found in mold grains and oils. , animal and plant foods.
At the same time, pay attention to avoid mildew on bamboo and wooden kitchen utensils, especially bamboo and wooden cutting boards, chopsticks, chopstick cages, rice spoons and other kitchen utensils. Washing and dry storage of dishes. If
Food is moldy
, even if the part is moldy, don’t eat the part that doesn’t look bad to save.
3. Avoid other environmental factors and related behavioral risk factors
Mainly include avoiding microcystins (microcystins, MC), quitting smoking, alcohol, preventing obesity and diabetes, and Be mindful of diet and nutrition.
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4. Timely screening for liver cancer
Screening of high-risk groups of liver cancer helps early detection, early diagnosis, and early treatment, and is an important measure to improve the survival rate of liver cancer patients.
According to the “Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2019 Edition)” issued by the National Health Commission of China, people at high risk of liver cancer should receive regular screening, including HBV Infections, HCV infection, chronic alcoholism (alcoholic liver disease), nonalcoholic steatohepatitis, consumption of aflatoxin-contaminated food, cirrhosis of multiple causes, and people with a family history of liver cancer. Also, men over the age of 40 are at greater risk and should also be screened.
How to detect liver cancer early?
How to stay away from liver cancer?
What are the “culprits” of liver cancer?
…
References
[1] Harriet Rumgay, et al., (2022). Global burden of primary liver cancer in 2020 and predictions to 2040. Journal of Hepatology, DOI: 10.1016/j.jhep.2022.08 .021.
[2] Liver cancer cases and deaths projected to rise by more than 55% by 2040. Retrieved Oct 10 ,2022,from https:https://medicalxpress.com/news/2022- 10-liver-cancer-cases-deaths.html
[3] Number of new cases and deaths from liver cancer predicted to rise by more than 55% by 2040. Retrieved Oct 10 ,2022,from https:https://www.iarc. who.int/fr/news-events/number-of-new-cases-and-deaths-from-liver-cancer-predicted-to-rise-by-more-than-55-by-2040/
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