How should azithromycin be used for mycoplasma infection? The doctor’s article tells you

2 days ago, an elder sister came to the doctor for gynecological diseases and told me that I have been taking azithromycin tablets for a month, but the infection has not completely improved, and asked to continue taking azithromycin tablets prescribed for one month , so that the disease can be completely cured. Can I continue to take Azithromycin Tablets? Today, Dr. Li will explain how to use azithromycin tablets correctly.

What is azithromycin?

Azithromycin is a semi-synthetic macrolide antibiotic. Commonly used azithromycin injections, capsules, tablets, granules and so on. Oral azithromycin is rapidly absorbed and can transport the efficacy of azithromycin to the site of inflammation. The effect after administration can be maintained for 35-46 hours, and the half-life of the dose can be excreted through the biliary tract with more than 50% of the original form, and about 4.5% of the original form can be excreted through the urine within 72 hours.

Azithromycin treatment indications

1, suitable for the treatment of acute pharyngitis and acute tonsillitis caused by Streptococcus pyogenes.

2, sinusitis, otitis media, acute bronchitis, and acute exacerbation of chronic bronchitis caused by sensitive bacteria.

3, pneumonia caused by streptococcus, pneumonia caused by Haemophilus influenzae and mycoplasma,

4, Urethritis and cervicitis due to Chlamydia trachomatis and non-multidrug-resistant Neisseria gonorrhoeae.

5. Skin and soft tissue infection caused by sensitive bacteria.

However, the treatment of these indications needs to be tested before the right medicine can be prescribed.

Adverse reactions of azithromycin

In many popular science about drugs Most of the articles will mention that all medicines have certain side effects, and azithromycin is no exception. Under normal circumstances, side effects after taking azithromycin are rare, mostly mild to moderate reversible reactions,

1, gastrointestinal tract Reaction is a common reaction during holidays, and common symptoms include diarrhea, nausea, abdominal pain, loose stools, and vomiting.

2, skin symptoms: rash, itching, etc. can be seen.

3 Other reactions include anorexia, vaginitis, dizziness, or dyspnea.

4, allergic bronchospasm.

5, abnormal taste.

6, nervous system symptoms, such as drowsiness and headache can be seen.

7, allergic reactions: arthralgia, angioedema, urticaria, photosensitivity.

8, causing arrhythmia and sinus tachycardia.

9, can cause acute renal failure.

10, can cause thrombocytopenia.

Moreover, it has been reported that azithromycin causes hepatitis and cholestatic jaundice, and occasionally causes liver necrosis and liver failure, with fatal reports!

However, as ordinary people, most of them do not know the effects of drugs on the body. According to clinical drug data, the application of macrolides Drugs of this class can impair the patient’s strength. I once encountered a patient who had symptoms of hearing loss after taking azithromycin, tinnitus, deafness, and also found that it could cause the patient’s abnormal taste.

Therefore, you must follow the doctor’s instructions before taking Doctor ordered medication!

Points to note when using azithromycin

Many people know that some medicines need to be taken before or after meals or on an empty stomach. Such requirements are mainly based on the nature of the medicine to determine the time of taking the medicine.

● Azithromycin is generally taken 1 hour before or 2 hours after meals, because if you choose to take it with food, it will affect the absorption of azithromycin.

● Azithromycin should be used with caution in patients with hepatobiliary system diseases, because the excretion of azithromycin is mainly excreted through the hepatobiliary system, so it may cause damage to the liver and gallbladder.

● If you have allergic angioedema or skin reaction disease while taking it, you should stop taking the medicine immediately and go to the hospital in time.

According to literature, in 2013 the US FDA issued a warning, Azithromycin can cause abnormal electrical activity in the heart, causing fatal arrhythmias. Higher risk of QT prolongation, hypokalemia or hypomagnesemia, tachycardia, and addition of antiarrhythmic drugs.

So, how to take medicine correctly?

Taking medicines is not something we can take every day like our daily meals. We all know that medicines are used to treat diseases. Scientific medicine can treat diseases, but if it is abused, it will be counterproductive. Azithromycin dosage:

Adult dosage:

● For the treatment of sexually transmitted diseases caused by Chlamydia trachomatis or sensitive Neisseria gonorrhoeae, only a single oral dose of 1 gram is required. That is, you only need to take it once, 1 gram at a time. For example, if the content is 0.25 grams, then you need to take 4 capsules to achieve the therapeutic effect.

The treatment of other infections: Take 0.5 grams of medicine on the first day, (that is, 2 capsules), and take it every day on the 2nd to 5th day 0.25g or 0.5g, taken once a day for 3 consecutive days.

Pediatric dosage:

The dosage for children needs to be calculated according to the weight of the child, because the growth of children is not yet perfect, and they are still in the growth and development stage, and the resistance of various organs to some drugs will cause some damage .

◆ Treatment of otitis media and pneumonia: Day 1, calculated by body weight, per day The required dose per kilogram is 10 mg (the maximum amount cannot exceed 0.5 grams per day), Day 2~Day 5, the daily dosage is 5 per kg In milligrams, it only needs to be taken once a day. (The maximum amount per day should not exceed 0.25 grams.)

● Treatment of infantile pharyngitis and tonsillitis, calculated per kilogram 12 mg per kg (the daily amount should not exceed 0.5 g), it is enough to take it only once a day for 5 consecutive days, or follow the doctor’s advice.

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How should azithromycin be used in the treatment of mycoplasma disease?

The treatment of mycoplasma infection with azithromycin depends on the type of mycoplasma and the site of infection. The course of treatment ranges from 1 to 3 weeks. For upper respiratory tract infection caused by Mycoplasma pneumoniae, the course of treatment is generally about 7 days. For lower respiratory tract infection caused by Mycoplasma pneumoniae, Such as bronchopneumonia and tracheitis, generally need to take about 2 weeks. Urinary tract infection caused by Ureaplasma urealyticum, Mycoplasma genitalium, Mycoplasma hominis, that is, mycoplasma infection transmitted through sex, generally requires more than 2 weeks of treatment. It is best to take it for about 3 weeks so that it can be effectively treated, and the recurrence rate will be relatively reduced. However, azithromycin has high drug resistance. If it is to treat mycoplasma infection in the genitourinary system, it is best not to choose azithromycin as the first choice. Antibiotic treatment.

Azithromycin is not a drug of choice for patients, if you Without sufficient understanding of azithromycin, it is best not to choose to apply it lightly. Because the application of azithromycin to treat diseases requires a sufficient amount and a full course of treatment; moreover, it is necessary to adjust the dosage application according to the condition. The efficacy of antibacterial drugs depends on the effective blood drug concentration. If the effective blood drug concentration cannot be reached, not only will the bacteria not be completely killed, but it will also increase the resistance of the bacteria.