Dian has a brother
Gout at a young age
Each seizure
Look at his distressed appearance
I always feel my joints hurt too
Today’s topic
Gout prefers boys
Is it because they like to eat and drink?
Statistics as of February 2016
The ratio of male to female gout patients in my country is 15:1[1]
This disproportion is really serious
But simply blame them for eating and drinking
Boys are also a bit wronged
Our bodies metabolize “junk” every day
Uric acid is one of them
It needs the kidneys and intestines to run regularly[2]
During garbage delivery
The difference between men and women comes out!
Androgens dominate in men
Women are estrogen and progesterone
On transporting uric acid waste
Androgens are the roadblock
It will stop the garbage truck from working
Estrogen is the opposite, it’s an accelerator
It can improve the transportation efficiency of uric acid waste
So after menopause when female hormones drop
The incidence of gout is similar to that of men[3]
Our bodies
Maximum uric acid waste is 1200 mg[2]
The human body produces 750 mg of uric acid waste per day[2]
Kidney Garbage Truck
Remove 500-1000 mg of uric acid per day[2]
When the balance between production waste and metabolic waste is broken
After the extra uric acid enters the blood
Start making waves
Blood uric acid levels are on the rise
The normal value of serum uric acid is 420μmol/L[2]
Be vigilant if it exceeds
When the saturation solubility is finally reached
Urate crystals will precipitate
When landing on joints and surrounding tissue
“Community Security” – inflammatory cells will be dispatched immediately
Fight with uric acid crystals
You will experience joint pain at this point
This is the gout attack
Body pain is already painful
What is more worrying is the lack of freedom to eat and drink
Brother Dian has sorted out the strategy for you
How do I eat and drink?
What to drink:
Boiled water, mineral water: At least 2000ml[4] per day (4 bottles of 500ml mineral water)
Milk: Low-fat and non-fat, especially, may reduce the risk of gout. Be careful not to treat lactic acid bacteria drinks as milk, if you drink the wrong one, gout will come to find fault[5]
NOT:
Wine or alcoholic beverages, no
Sweet drinks, no! Just think about cola, fruit juice, vitamin drinks, don’t move your mouth
Fish soup[6], chicken soup, seafood soup[7] stay away
Dian doesn’t want to talk about eating and drinking all the time
But gout is not free to eat and drink because of purines!
Uric acid comes from it
20% of purines are ingested in vitro and 80% are produced endogenously
However, this 20% control is key
Uric acid can be reduced by 10% to 18% by controlling diet[8]
Of course among first-degree relatives
Friends with hyperuricemia or gout
Pay extra attention to your diet
Do regular checkups, don’t relax
Final crash
Controlling your weight and exercising is also crucial
Starting tonight
Run for 30 minutes with Dian every day
Like and watch
Thank you~
Reviewer: Yang Tiesheng
Chief Physician of the Department of Rheumatology and Immunology, Peking University People’s Hospital
References
[1] Zeng Xiaofeng, Chen Yaolong. 2016 Guidelines for Diagnosis and Treatment of Gout in China [J]. Chinese Journal of Internal Medicine, 2016, 55(11): 892-899.
[2]Chen Haozhu, Lin Guowei, Wang Jiyao, et al. Practical Internal Medicine. 15th Edition People’s Health Publishing
Editor.2017.2656-2670.
[3] “2017 White Paper on Report on the Status of Gout in China”
[4]WS/T 560―2017, Dietary guidance for patients with hyperuricemia and gout[S]. Beijing: National Health and Family Planning Commission of the People’s Republic of China, 2017.
[5] Becker M A, MD; Tuhina Neogi, MD, etal. Lifestyle changes and other strategies to reduce the risk of gout flares and progression [J]. UpToDate, 2022 (Special Issue 105886 Version 15.0 .zh-Hans.1.0): https:https://www.uptodate.cn/contents/zh-Hans/lifestyle-modification-and-other-strategies-to-reduce-the-risk-of-gout-flares- and-progression-of-gout?search=%E5%92%96%E5%95%A1%20%E9%99%8D%E4%BD%8E%E5%B0%BF%E9%85%B8&source=search_result&selectedTitle =4~150&usage_type=default&display_rank=4#H2650547312.
[6]Wang Xinyan, Ling Yun, Sun Li, et al. Effects of boiling and heating on the contents of four purines in fish meat [J]. Food Science and Technology, 2008, 33(11):4.
[7]Wang Xinyan, Ling Yun, Chu Xiaogang, et al. Changes of four purine contents in meat products during boiling [J]. Food Science, 2008, 29(7):3 .
[8] Li Qianhua, Dai Jie. Updating new viewpoints on the dietary treatment of gout[J]. Chinese Journal of Rheumatology, 2015, 19(07): 433-434.
Author: Guo Qian | Illustrator: Gao Yuanyuan
Editors: Guo Qian, Wu Jiaxiang, Wang Yan
Proofreading: Wu Yihe | Typesetting: Li Yongmin
Operation: Han Ningning | Coordinator: Zhao Yanan