Source: Internet (Liaocheng University School of Medicine. Liaocheng Vocational and Technical College; Li Yanhua, Liu Fengzhen, Cao Yinguang)
< p data-track="3">I. Summary
In this study, we successfully prepared zirconium phosphate-supported silver antibacterial composite resin. SEM results showed that the surface particles were uniformly dispersed. EDS analysis indicated that the zirconium phosphate-supported silver antimicrobial was successfully incorporated into the composite resin. The initial curing rate of the zirconium phosphate-loaded silver antibacterial agent Durafil composite resin was obtained by FT-IR analysis.
2. Background
In recent years, antibacterial composite resins have been favored by researchers due to their good mechanical properties and excellent aesthetic repair effects.A wide range of materials are used in the field of oral applications. A large number of studies have confirmed that zirconium phosphate-supported silver (LZB-GC) is a silver-based antibacterial agent with zirconium phosphate (Zr(HPO4)2) as the carrier, with ideal antibacterial properties and activity. The antibacterial agent has also made important improvements to the discoloration problem of silver ions, and has good discoloration resistance. Liu Wenjuan et al. added LZB-GC antibacterial agent to Alginate Impression Materials at different mass ratios, and took the blank group as a control to test its antibacterial effect on Staphylococcus aureus by the Film Contact Method. and antibacterial properties of Escherichia coli. The study found that increasing the amount of LZB-GC antibacterial agent, S. aureus and E. The antibacterial rate of coli also increased accordingly. In addition, Liu Bin et al. added zirconium phosphate-loaded silver antibacterial agent in different proportions to the base material of oral denture to test the mechanical properties of the material. The study found that when the addition amount is 2%-3%, the mechanical properties are enhanced and the antibacterial effect is good.
It is of great research value in the field of oral cavity to find a method to prepare a new type of antibacterial composite resin by adding an antibacterial agent to the composite resin. Work. In this study, mechanical stirring (Mechanical Stirring) and ultrasonic dispersion (Ultrasonic Dispersion) were used to disperse zirconium phosphate silver-loaded antibacterial agent in Durafil composite resin at a mass ratio of 1.5% to prepare zirconium phosphate-loaded silver antibacterial agent. composite resin.
III. Experimental part
1. Experimental Materials and Instruments
Zirconium phosphate silver-loaded antibacterial agent, Durafil composite resin, anhydrous ether, silane coupling agent KH570;
Electronic balance, magnetic stirrer, KQ‐300DE CNC ultrasonic cleaner, RE‐52 rotary evaporator, glass dropper, agate mortar, light curing machine.
2. Experimental steps
2.1. Preparation of zirconium phosphate loaded silver antibacterial composite resin
LZB The preparation process of ‐GC antibacterial composite resin is shown in Figure 1. In this experiment, 30 mg of silver-loaded zirconium phosphate antibacterial agent and 2 g of Durafil composite resin were weighed to prepare a 1.5% antibacterial composite resin by mass. The experimental process is as follows: first, the distilled water in Anhydrous Diethyl Ether is completely removed by reflux technology (Reflow Technology), then 30 mg of zirconium phosphate-loaded silver antibacterial agent is put into the flask, and 5 mL of anhydrous ether is added to the above flask. , placed on a magnetic stirrer, stirred evenly, and evenly mixed by ultrasonic vibration; weighed 4 g of Durafil composite resin and placed it in an agate mortar, and poured the mixture of zirconium phosphate-supported silver antibacterial agent and anhydrous ether under shading conditions. into the composite resin, then add a drop of silane coupling agent KH570, grind evenly, and make the mixture dissolve completely. Finally, it was transferred to a flask, magnetically stirred for a certain period of time, and then ultrasonically mixed for a period of time until it became a milky white suspension. The flask was tightly wrapped with tinfoil, and rotary-evaporated for a period of time in the dark until the anhydrous ether was completely evaporated. The composite resin was scraped out with a spatula and placed in a light-proof vessel for use in subsequent experiments.
2.2, Sample Testing and Characterization
The distribution of LZB‐GC antimicrobial agent in Durafill composite resin was observed by scanning electron microscope (SEM). The relative contents of Ag and P elements on the surface of LZB-GC antimicrobial agent were analyzed by electron energy dispersive spectrometer (EDS). FTIR was used to reflect the relative change of aliphatic C=C absorption intensity before and after curing of the composite resin, and the curing rate (RC) was calculated according to the curing formula.
IV. Results and Discussion
1, SEM characterization and EDS analysis
Figure 2(a) shows the SEM results of the surface of the zirconium phosphate-supported silver composite resin. It can be seen from the figure that there are some cube-like particles of different sizes and evenly distributed on the surface of the resin. It can be seen that: by this experimental method, the zirconium phosphate-supported silver antibacterial agent and the Durafil composite resin can be successfully mixed together uniformly without agglomeration. It can be seen from Figure 2(b) that the surface of the zirconium phosphate-supported silver composite resin contains P and Ag elements, which further indicates that the zirconium phosphate-supported silver antibacterial agent has been successfully mixed into the composite resin.
2. FTIR analysis
FTIR is a measure of the curing rate of composite resins (Photopolymerization Efficiency) has been used for many years and is currently a very reliable and sensitive measurement method. Analysis of Durafill composite resin before and after curing vinyl at 1640 cm-¹, C=C stretching vibration absorption peak intensity, curing rate 100% minus the proportion of C=C. Figures 3(a) and (b) are the FTIR analysis spectra before and after curing. It can be seen from the figure that the area of the vibration absorption peak at 1640 cm -¹ in the figure is relatively reduced after curing.
2. Curing rate
The curing rate of the composite resin is calculated according to the following formula
V. CONCLUSION
This study uses mechanical Stirring and ultrasonic dispersion techniques successfully mixed the zirconium phosphate-supported silver antimicrobial agent into the Durafil composite resin. SEM results showed that the surface particles were uniformly dispersed. EDS analysis indicated that the zirconium phosphate-supported silver antimicrobial was successfully incorporated into the composite resin. The change of absorption peak area of C=C before and after curing was analyzed by FT-IR, and the initial curing rate of Durafil composite resin was obtained.
Therefore: Zirconium phosphate with silver-loaded antibacterial agent modified and mixed into Durafil composite resin can effectively strengthen the base of oral denture The mechanical properties and antibacterial properties of the support material, and it has good discoloration resistance.