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Once a patient is diagnosed with schizophrenia, most of them will be told that they need to take medicine for life. Although the price of a single drug treatment is acceptable, by observing the schizophrenia group, it can be found that the patient has been unemployed for a long time due to illness, and the condition is repeatedly difficult to control. Unable to extricate themselves, will greatly increase the family’s economic and spiritual burden. Isn’t there a treatment method that can eliminate mental illness, help patients reintegrate into society, and reduce the burden on families?
The answer is of course yes, the functional neurology department of our hospital adopts the fifth generation of brain stereotaxic surgery For schizophrenia, the disappearance rate of positive symptoms in postoperative patients accounts for about 95%. The operation has a high elimination rate of various positive symptoms, such as hallucinations, delusions, abnormal behaviors, family hostility, violent attacks, etc. The symptoms are completely relieved; postoperative patients About 85% of the negative symptoms disappear, and the operation also has a good effect on negative symptoms such as depression, apathy, loneliness and withdrawal, and fear.
Case: Male patient, 23 years old, with a history of schizophrenia for more than 8 years
The patient developed insomnia without obvious incentive in 2013, suspected that someone had poisoned the meal, and heard someone out of thin air He spoke ill of him, talked to the voices he heard, often went out and ran around for no reason, talked to himself, laughed to himself, and lived a passive life. At that time, he went to the local psychiatric hospital and was diagnosed with “schizophrenia”. He was given oral “risperidone” “And other drug treatment, the patient was hospitalized for 1 month and discharged, and after discharge, the drug was irregularly taken, and the symptom control was good and bad. In 2016, the patient’s condition relapsed, he talked a lot, boasted that he was rich, drank and surfed the Internet, and spent money lavishly. When his parents discouraged him, he lost his temper with his family, threw things, ran away from home without saying hello, and was hospitalized 8 times. After taking a variety of antipsychotic drugs (clozapine, amine fenapride, lithium carbonate, amine fenapride, olanzapine) for symptomatic treatment, regular, sufficient amount, and full course of medication, the condition is still repeated and aggravated.
At the beginning of 2022, the patient and his family went to the functional neurology department of our hospital for treatment, intending to seek surgical treatment. According to the preliminary assessment of the outpatient doctor, the patient is now sensitive and suspicious. To harm him, hear voices out of thin air, feel scared and nervous, feel flustered and have headaches, be short-tempered, irritable, hostile to family members, beat and scold family members, throw things, repeatedly check whether the door is closed, live passively, deny that he is sick, social function significantly damaged.
After the operation, the patient’s vital signs were stable, and there was no obvious discomfort. According to the description of the family members, the patient’s preoperative symptoms such as sensitivity, paranoia, auditory hallucinations, anxiety and tension, irritability, and self-talk were effectively controlled, and the palpitation and headache disappeared. After reaching the clinical cure standard, he was discharged from the hospital.
Schizophrenia is a group of psychiatric disorders of unknown etiology caused by multiple factors, which is associated with genetic, neurodevelopmental, Neurobiochemical and psychosocial factors. Among them, neurobiochemical research has attracted much attention. The mechanism of fifth-generation stereotaxic surgery for psychiatric disorders is to modulate neurotransmitters in the central nervous system to remove or control psychiatric symptoms. The nerve center that dominates mental activities such as thinking, emotion, cognition, and behavior of the human brain is recognized as located in the limbic system consisting of “limbic lobe, thalamus, hypothalamus, amygdala, and cingulate gyrus.” The fifth generation The theoretical basis of brain stereotaxic surgery for the treatment of schizophrenia is to select the neural nuclei in the limbic system for different combinations of neural nuclei targets according to the clinical psychiatric symptoms of the patient, and then adjust the distribution and content of neurotransmitters, so that Restoring a new balance to eliminate or reduce symptoms of schizophrenia.