About 160,000 people are deprived of their lives by gastric cancer every year in my country. The occurrence of lung cancer is closely related to Helicobacter pylori. Treatment to eliminate Helicobacter pylori from the body and prevent disease from occurring.
So what are the abnormalities after the stomach is infected with Helicobacter pylori? Let’s take a look together and see which method needs to be used to completely kill Helicobacter pylori.
01
First of all, let’s understand what is Helicobacter pylori and how it survives of?
Helicobacter pylori is a Gram-negative bacillus,the appearance is multi-flagellate, the terminal Blunt, spiral curved, commonly found on the surface of gastric mucosa or in gastric pits, but does not invade the intrinsic glands of the mucosal layer, and is the only microbial species known to be able to survive in the human stomach.
The pathogenic mechanism of Helicobacter pylori includes:
< p data-track="7">1. Helicobacter pylori passes through the gastric mucus to reach the surface of the gastric mucosa, and at the same time inhibits the phagocytosis of white blood cells, so as to survive at a certain value.
2. Secretion of urease cytotoxin, related proteins and cell vacuole toxin, etc., which damage the gastric mucosa Barrier, extreme diseases include gastritis, gastric cancer, peptic ulcer, lymphoid hyperplasia, gastric lymphoma, etc., and is listed as the first type of biological cancer factor by the World Health Organization.
Currently people and people The oral-oral or fecal-oral route is the main transmission route of Helicobacter pylori. The common symptoms of Helicobacter pylori infection include fullness, discomfort or pain in the upper abdomen after eating, often accompanied by other adverse symptoms, such as belching, abdominal distension and nausea. Acid, loss of appetite, etc.
If the Helicobacter pylori eradication treatment is carried out, the corresponding incidence rate will decrease, and the treatment effect will increase again, especially Peptic ulcer is a very difficult medical disease with a high recurrence rate.
Since the discovery of Helicobacter pylori eradication treatment, the recurrence rate of peptic ulcer has gradually decreased, which means The eradication rate of Helicobacter pylori is improved, and the recurrence rate of peptic ulcer is reduced at the same time, which brings great benefits to reduce the number of patients and medical treatment process, and reduce medical expenditure.
Helicobacter pylori
Helicobacter pylori generally likes to grow in an acidic environment, Helicobacter pylori The key to the survival conditions of Helicobacter pylori is the acid-alkaline environment. Helicobacter pylori can integrate into the environment of gastric juice and survive in the stomach of the human body. Alkaline body, then the survival rate of Helicobacter pylori will gradually decrease.
When many people go to the hospital to treat Helicobacter pylori, they will apply ozone therapy, which is aimed at Helicobacter pylori Bacteria effect is good, can effectively eliminate Helicobacter pylori.
The prevention of Helicobacter pylori infection is mainly through diet prevention, try not to interact with other infections People with diseases can have too close contact. Generally, daily contact is not a big problem. Usually, pay attention to eating as regularly as possible, lightly, and not overeating.
02
There is “Helicobacter pylori” in the stomach, what are the abnormalities in the body? Early knowledge, early benefit
1. Bad breath: For some patients with gastric infection of Helicobacter pylori For humans, there will be obvious bad breath, mainly because Helicobacter pylori will survive on dental plaque, so when Helicobacter pylori is infected in the oral cavity, it will cause some food residues and produce odorous carbides, thus Bad breath.
< span>2. Stomach pain: When there is Helicobacter pylori in the stomach, there will be a feeling of stomach pain. This is mainly because the Helicobacter pylori in the body continuously stimulates the stomach, short Stomach pain that occurs during the period may be caused by unhealthy conditions. If the pain persists, sometimes there will be a dull pain or tingling sensation, and there may be gastric ulcer in the stomach.
Helicobacter pylori lives in the stomach and will continue to irritate the gastric mucosa, thereby damaging the gastric mucosa and causing gastric Ulcers, a common symptom that occurs when you have stomach ulcers, are a dull ache or tingling sensation in your stomach.
3. Acid reflux : People with stomach problems often have acid reflux. When Helicobacter pylori grows, it will lead to increased gastrin in the body. When gastrin increases, it will stimulate the gastrointestinal mucosa, resulting in increased gastric acid. To neutralize gastric acid, in the final analysis, it is because of the existence of Helicobacter pylori in the body. Only by removing this bacterium can the body become healthier.
4. Abdominal fullness: abdominal fullness is mainly caused by Helicobacter pylori destroying the epithelial cells of the gastric mucosa, causing Insufficient gastric acid secretion, abnormal digestion of food in the gastrointestinal tract, symptoms such as abdominal fullness, belching, and loss of appetite, are mainly common in chronic gastritis.
5. Sudden weight loss: Under normal circumstances, sudden unexplained weight loss may be caused by Helicobacter pylori, because Helicobacter pylori can disrupt the normal digestion and absorption function of the human body. If it is diagnosed as Helicobacter pylori, the doctor recommends drug treatment to improve conditioning, except You also need to pay more attention to your diet outside of taking medicine.
03
Quadruple therapy for Helicobacter pylori
Quadruple therapy for the treatment of Helicobacter pylori is the main method for eradicating Helicobacter pylori, usually using 2 kinds of antibiotics + 1 kind of proton pump inhibitor + 1 kind of bismuth.
1. Antibiotics: Antibiotics play a major role in the eradication of Helicobacter pylori. Commonly used drugs include clarithromycin, amoxicillin, metronidazole, tinidazole, levofloxacin, furazolidone, tetracycline, etc. Due to the different antibiotic resistance in different regions, the course of antibiotic treatment The choice should be based on the local drug resistance situation.
2. Proton pump inhibitors: due to the presence of gastric acid in the stomach, it is an acidic environment, and antibiotics are in an acidic environment Therefore, it is necessary to combine proton pump inhibitors to suppress gastric acid, increase the pH value in the stomach, and exert the effect of eliminating Helicobacter pylori. Commonly used drugs include esomeprazole, omeprazole, and lansol Larazole, Pantoprazole, Rabeprazole, Ilaprazole, etc.
3 Bismuth: bismuth It is a gastric mucosal protective agent, which precipitates in the stomach and forms a diffuse protective layer covering the damaged gastric mucosa to promote mucosal regeneration and ulcer healing. Common drugs include bismuth potassium citrate and bismuth pectin.