“Today, are you depressed”?
It was originally just a joke, but now, this sentence has become a true portrayal of many people.
In February 2019, Professor Huang Yueqin of Peking University Sixth Hospital and others published online in The Lancet Psychiatry Research article reporting prevalence data from the China Mental Health Survey (CMHS), the first nationwide epidemiological survey of mental disorders in China.
The survey showed that the lifetime prevalence of depression (the proportion of the total population who experienced depression in their lifetime) was 6.8%, and the 12-month prevalence rate (depression within 12 months) was 6.8%. The proportion of patients with depression in the total population) was 3.6%. Based on this calculation, more than 95 million Chinese have suffered from depression in their lifetime.
In other words, one out of 13-15 Chinese people suffers from depression. Obviously, as a common disease, depression has become the second largest “killer” of human beings…
The composition and usage of fluoxetine hydrochloride dispersible tablets
For depression, it depends on Invisible and intangible, different from traditional diseases, especially in traditional Chinese concepts, depression may be seen by others as a hypocritical, and it will be fine in a few days, so it is often ignored.
As a result, most people with mental disorders in China have become “not seeking medical treatment when they are ill” and choose to endure alone, which not only leads to a decline in the quality of life, but also may cause tension in family and interpersonal relationships.
Of course, depression is not incurable, and drug treatment is an option for many patients with depression. Prozac’s fluoxetine hydrochloride dispersible tablets play a role in relieving depression.
Fluoxetine hydrochloride dispersible tablet is an oral prescription drug, the main ingredient is fluoxetine hydrochloride. It is suitable for treating symptoms such as:
Treatment of depressive symptoms, with or without accompanying symptoms of anxiety. The consensus reached by the WHO is that antidepressants should be continued for at least 6 months.
Also used to treat obsessions and compulsions with or without depression.
In addition to the above two symptoms, fluoxetine hydrochloride dispersible tablets can even be used to relieve bulimia and cathartic behavior with or without depression.
Adverse reactions and precautions of fluoxetine hydrochloride dispersible tablets
It is a three-point drug, so what are the adverse reactions of fluoxetine hydrochloride dispersible tablets? Let An An introduce it to you:
In terms of skin system:
Allergies (such as itching, rash, rubella, allergic reactions, vasculitis, serum reactions, facial edema may occur) Wait).
In the digestive system:
Gastrointestinal disturbances (eg, diarrhea, nausea, vomiting, indigestion, difficulty swallowing, inversion of taste), dry mouth, etc. Even abnormal liver function tests are rare, and of course hepatitis is rarely reported.
Nervous system:
Headache, sleep disturbances (eg, abnormal dreams, insomnia, drowsiness), dizziness, anorexia, fatigue, euphoria, transient abnormal movements (eg, convulsions, ataxia, tremors, myoclonus, etc.), spastic seizures, and rare psychomotor restlessness/akathisia.
Psychiatrically:
Having hallucinations, manic reactions, confusion, agitation, anxiety and related symptoms (eg, nervousness), reduced ability to concentrate and think (eg, depersonalization) , panic attacks, serotonin syndrome is extremely rare, suicidal ideation and behavior (these symptoms can be due to underlying medical conditions), etc.
Therefore, when taking fluoxetine hydrochloride dispersible tablets, there are two major precautions that you must pay attention to:
The first is to warn people under the age of 18. Because in clinical trials, antidepressant-treated groups were more likely to develop suicide-related behaviors (suicide attempts and suicidal thoughts) and hostile behaviors (mainly aggression, oppositional behavior, and anger) than placebo control groups.
Second, it is recommended to conduct regular inspections for the occurrence of mania and hypomania. If mania occurs, discontinue the drug immediately. Physicians should discuss the pros and cons of treatment with the child/adolescent patient or their parents in detail when prescribing.
References:
1. Shao Qingxiang, Li Chuan, Zhang Meiyun, et al. Bioequivalence study of fluoxetine hydrochloride dispersible tablets and capsules[J]. China Journal of New Drugs, 2003, 12(4):277-281.
2. Anonymous. Prof. Huang Yueqin’s team released the results of “Prevalence of Mental Disorders in China: Epidemiological Research” [J]. Journal of Peking University: Medical Science Edition, 2019, 51(2):1.
3. Wang Suping, Wang Changding, Lin Lizhen. Determination of fluoxetine hydrochloride dispersible tablets by HPLC[J]. Journal of Contemporary Medicine, 2011, 09(7):241-241.
4. Wang Suping, Lin Lizhen. Determination of Fluoxetine Hydrochloride Dispersible Tablets by High Performance Liquid Chromatography[J]. ), 2011, 09(8):235-235.
5. Lu Libo, Zhang Xiaoling. Determination of Fluoxetine Hydrochloride Dispersible Tablets by High Performance Liquid Chromatography[J]. Science and Technology Entrepreneur, 2012 , 000(006):357.
6. Wang Jinhuan. A controlled clinical study of sertraline hydrochloride dispersible tablets and fluoxetine in the treatment of post-stroke vascular depression [J]. China Minkang Medicine, 2012 , 24(21):2.
Part of the figure is from the Internet
Reviewer/Zou Yuhua