Author: Gcplive
Source: Center for Drug Evaluation< /p>Infectious diarrhea(also known as acute gastroenteritis)refers to diarrhea caused by intestinal infections of various pathogens . At present, there are still problems such as unreasonable application of antibiotics in the treatment process. Here are at least 4 things you need to know about diarrhea in children! 1. Common pathogens of infectious diarrhea in childrenCommon pathogens include rotavirus, norovirus, Shigella, non-typhoid Salmonella, jejunum Campylobacter, Escherichia coli, etc., among which viral infections are the most common. Shigella, non-typhoid Salmonella, Campylobacter jejuni and Escherichia coli are all G-bacteria. Shigella is also known as Shigella. II. Clinical characteristics of common acute infectious diarrheal diseasesrotavirus Such as viruses and toxigenic E. coli bacteria often cause watery stools and are self-limiting. III. Anti-infective treatment for children with acute infectionwatery diarrhea It is mostly caused by viral or non-invasive bacterial infections, and generally neither antibacterial drugs nor antiviral drugs are used (currently, there is a lack of specific antiviral drugs). Pus and bloody stoolsmostly invasive bacteriainfection, and antibiotics should be given . Reminder:Some bacteria, by means of flagella or fimbriae, interact with intestinal mucosal epithelial cells. Binds to the receptor, colonizes and reproduces only on the intestinal mucosal surface. There are some bacteria that further invade the intestinal epithelial cells to multiply and spread to the adjacent epithelial cells, causing the intestinal epithelial cells to die. Some bacteria can penetrate the intestinal epithelium and invade the blood.
Common diarrhea-causing Escherichia coli and anti-infective treatment:Reminder:Endotoxin is a component of the cell wall of G-bacteria, and usually does not show toxic effects when the bacteria survive. Only when the bacteria die and lyse, the endotoxin is released and exerts a toxic effect. If antibiotics are used after the bacteria multiply, the disease may be aggravated by the massive release of endotoxin. IV. Commonly used drugs for children with acute infectious diarrhea1. Oral rehydration salts (Ⅲ)< span>Enough oral fluids should be taken from the onset of diarrhea to prevent dehydration, and oral rehydration salts (III) should be selected, until the diarrhea stops. 2.montmorillonite powdermontmorillonite To shorten the course of acute watery stoolin children and reduce the frequency and volume of diarrhea. 3. Zinc supplementation therapyin areas with high zinc deficiency and nutrition Zinc supplementation can shorten the duration of diarrhea in children aged 6 months to 5 years in children with adverse reactions.. 4. Probioticsprobiotics may shorten the duration of diarrhea and The length of hospital stay can be selected as appropriate.
Main references:
National Health Commission. Guidelines for the diagnosis and treatment of acute infectious diarrhea in children (2020 edition)< /p>
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