urgent! If you can't get the nine-valent and quadrivalent "cervical cancer" vaccine, do you need a domestic bivalent vaccine?

The importance of HPV vaccination must be familiar to friends who have been following Zhimei for a long time.

Cervical cancer is the second most common cancer among women in my country, and among many cancers, it is the only cancer that can be clearly identified and prevented in advance.

The country is already vigorously promoting the universalization of cervical cancer vaccination. However, the quadrivalent and nine-valent vaccines in many places are “hard to find”.

I’ve been waiting for a long time, but I still can’t get an appointment for the quadrivalent or nine-valent vaccine, what should I do? Do you need a bivalent vaccine?

Let’s talk about the conclusion first: There is no need to be obsessed with 9 valences. The principle of vaccination is “early vaccination, early protection, and early benefit”.

Instead of looking forward to the quadrivalent and nine-valent vaccines that are difficult to make an appointment, it is better to vaccinate the bivalent vaccine that is available and protect yourself from now on.

The domestic vaccine has high protection rate and few adverse reactions

Many people worry that the domestic bivalent vaccine is not as effective as other vaccines in protection, and this doubt can be dispelled as soon as possible.

According to the clinical trial analysis report[1,2], the performance of domestic vaccines in clinical trials is remarkable:

● In terms of preventing HPV16 and 18-related precancerous lesions, the protection rate is comparable to that of foreign quadrivalent and bivalent HPV vaccines;

● In terms of efficacy in preventing persistent infection of HPV16 and 18, the protection rate is comparable to that of foreign quadrivalent and bivalent HPV vaccines, and the adverse reactions are mild.

The price of domestic bivalent vaccine is more “people-friendly”

The domestic bivalent HPV vaccine is also much cheaper than the imported vaccine (the total cost of 3 injections is just over 1,000 yuan).

You don’t think “expensive is good”. The price of domestic bivalent vaccines is close to the people, mainly because of different production technology systems.

● The domestic HPV vaccine adopts Escherichia coli production technology, and the cost is relatively low, so the price is relatively economical.

● The imported HPV vaccine adopts the production technology system of Saccharomyces cerevisiae, and the cost is relatively high.

But no matter what kind of production technology it is, it is registered and approved by the State Food and Drug Administration and is trustworthy.

The production capacity of domestic vaccines is high and the supply is sufficient

The domestic “Escherichia coli factory” has the advantages of low cost, fast production speed and high output. Therefore, domestic bivalent vaccines are also used in the immunization programs of many provinces, cities and regions.

In addition, for girls aged 9-14, only 2 doses of vaccination can achieve the same preventive effect as 3 doses of adult vaccination, which saves money and worry.

At present, domestic HPV vaccines can be reserved in most areas. Zhimei has organized several appointment methods for you, and you can choose at will as needed:

● Make an appointment at the local vaccination clinic, CDC;

● Make an appointment on the official APP or WeChat account of the local hospital;

● Go to the community health service center or hospital where you live for consultation and make an appointment for vaccination;

● Call the 12320 health hotline around the country for enquiries.

Generally speaking, the HPV vaccine is very safe. Whether it is a domestic vaccine or an imported vaccine, everyone can rest assured to vaccinate and prevent it early.

01. I have already been vaccinated with bivalent and quadrivalent, can I still want to inoculate with ninevalent?

Not necessary.

At present, these three types of vaccines can play a preventive effect after vaccination, and repeated vaccination is of little significance [3].

But if you insist on getting vaccinated, you can get a higher-priced vaccine one year after completing the bivalent vaccination program if you meet the indications for vaccination.

02. One or two doses of bivalent and quadrivalent vaccines have been vaccinated. Can the second and third doses be vaccinated with nine-valent vaccines?

It should be as consistent as possible, and not obsessed with nine valences[4].

03. If the child is between 9 and 15 years old, should he be vaccinated with the bivalent or quadrivalent vaccine first, or should he wait until the child is 16 years old to receive the 9-valent vaccine?

Early vaccination is better than later vaccination.

Studies have shown that no matter which of the three vaccines are vaccinated, the vaccine elicits more antibodies in women aged 9-15 than in women aged 16-26 2 times [5].

In other words, the same vaccine is more protective against younger women.

Instead of expecting “possibly better” protection from the 9-valent vaccine in the future, it’s better to get vaccinated as soon as possible for peace of mind.

Again, the vaccine that can hit your body now to protect you is a good vaccine, compared to a vaccine that may work in the future. Early vaccination, early benefit.