The kidneys are the powerful organs of metabolism and detoxification in the human body, with strong compensatory properties. After digestion and absorption, the food, medicines and other imported things that we usually eat need to be filtered by the kidneys. It is eventually metabolized out of the body with urine.
The kidney is very compensatory, but it is also very fragile. If the protection of the kidneys is not paid attention to at ordinary times, it will cause kidney disease, resulting in the decline of all aspects of kidney function.
Simple understanding of the “development history” of chronic kidney disease!
Chronic kidney disease is mainly manifested in the inflammatory response stage in the early stage, also known as the renal compensatory stage. At this stage, the kidneys still have strong compensatory properties, and the body will not experience obvious symptoms. symptoms. However, if it is allowed to develop, kidney function will gradually fail, and eventually it will develop into kidney failure.
Most nephritis progresses to renal failure, which generally goes through 3 stages:
Nephropathy stage 1 and stage 2 is the kidney Compensation stage – stage 3 of renal disease is the stage of decompensation of renal function – stage 4 of renal disease is the stage of renal failure. Some types of nephropathy can be well controlled in the process of development, develop relatively slowly, and may not suffer from renal failure for decades; but some types of nephropathy progress rapidly, the deterioration of renal function is rapid, and the risk of renal failure is higher.
So, what are the symptoms of kidney disease friends who are more likely to develop kidney failure or even uremia?
1. The pathological type of nephropathy is severe, leading to rapid deterioration of renal function. Relatively poor ones such as focal segmental glomerulosclerosis, membranous proliferative glomerulonephritis, Diabetic nephropathy, amyloid nephropathy, etc.;
2. Renal insufficiency was found at the time of discovery, creatinine increased over 440, and glomerular filtration rate decreased significantly;< /p>
3. Long-term 24-hour urine protein quantification is higher than 1 g, and the treatment effect is poor;
4. Obvious complications of hypertension , and the blood pressure continues to rise above 130/80, and it is difficult to come down.
For most people, kidney disease can be maintained and controlled as long as it is diagnosed and treated in time. Except for the first one, the pathological type of kidney disease cannot be predicted and determined, the other three aspects including urine protein and high blood pressure are basically controllable as long as they are detected early.
The key to the prevention and treatment of renal failure in kidney disease is often prevention and early detection.
So, what are the obvious signs of early kidney disease? You must understand
edema in both lower extremities and ankles
Eedema is one of the most common signs in the body. The kidneys play a key role in regulating the balance of the body, so it is important to be alert to renal function in the event of edema. Among them, pitting edema occurred in both lower extremities and ankles, 80% of which were related to nephropathy. The pitting edema is manifested as a pit when pressed, and it is not easy to bounce back. People with these conditions should pay attention to the damage of kidney function.
Urine foam and decreased urine output
Under normal circumstances, the urine foam is large and dissipated in seconds, and the urine foam caused by kidney disease Most of them are small and difficult to dissipate, and exist for a long time, which is a typical symptom of urinary protein. The presence of protein in the urine is mainly due to glomerular filtration problems, and kidney problems are suspected first.
Decreased urine output is also one of the warning signs of kidney disease. Under normal circumstances, the daily urine output exceeds 1000ml and the number of toilet visits is 7 or 8 times. When the kidneys are damaged, toxins are filtered out, the urine formed naturally decreases, and the amount of urine excreted decreases significantly.
No history of high blood pressure but sudden increase
No high blood pressure, but sudden dizziness, headache, blood pressure detected Raise more than 130/80, pay attention to vigilance. When kidneys are damaged, blood flow slows, pressure in blood vessels increases, and high blood pressure develops.
Itchy skin
After kidney damage, some toxins cannot be metabolized, deposited in blood vessels, and will permeate after a long time into the epidermis, causing itching of the skin. Usually if there is no skin disease, long-term itching of the skin should also be paid attention to.