內容目錄
The total number of adults with diabetes in China is as high as 140 million, of which type 2 diabetes accounts for the majority, but only 16.5% of the patients have achieved blood sugar control. At the recent media conference on “High Standards, Benefit Control, and Benefit New Era”, the reporter learned that the world’s first basal insulin GLP-1RA injection was launched, which is suitable for adult type 2 diabetes patients with poor blood sugar control. Sugar is of high quality. Professor Mu Yiming, director of the Endocrinology Department of the First Medical Center of the PLA General Hospital, pointed out that in order to achieve the ideal blood sugar control goal for diabetic patients, in addition to lowering blood sugar, they should also pay attention to the stability of blood sugar and the safety of lowering blood sugar, so as to achieve “high-quality compliance”.
The event site of the media conference of “High Standard, Benefit Control, and Benefit New Era”
100 years ago, the discovery of insulin made the Diabetes has changed from an incurable disease to a manageable disease. In the past 100 years, hypoglycemic drugs have experienced rapid development, but the blood sugar control of patients with diabetes still faces many challenges. From the perspective of the patients themselves, factors such as poor pancreatic islet secretion capacity, high blood sugar fragility, and complications with the prolongation of the disease course may all lead to Increase the difficulty of treatment; from the perspective of the treatment plan, it is necessary to effectively reduce blood sugar while taking into account the safety issues such as the risk of hypoglycemia.
For diabetic patients, frequent and excessive blood sugar fluctuations are even more serious than persistent hyperglycemia, which will continue to damage vascular endothelial cells throughout the body, increase the risk of diabetic complications, and may cause blindness, Serious consequences such as kidney failure, heart attack, stroke and lower limb amputation not only affect the quality of life of patients, but also increase the economic burden on families and society.
Therefore, high blood sugar control is the first priority of blood sugar management in diabetic patients. Controlling blood sugar to the target as soon as possible will help reduce or delay the occurrence of diabetes complications. Professor Yoshiaki Mu emphasized that for patients with poor control of oral hypoglycemic drugs and basal insulin in actual treatment, such as patients with type 2 diabetes, blood sugar management needs to achieve real “high-quality standards” – blood sugar control standards, blood sugar control stable, Safe blood sugar control, reduces the risk of hypoglycemia, and avoids the side effects of weight gain.
How to achieve high blood sugar control, scholars have conducted many studies. The world’s first basal insulin GLP-1RA injection, which was launched recently, has been affirmed by many domestic and foreign diabetes guidelines for its efficacy and safety, and has become an important choice for diabetes treatment. The “Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2020 Edition)” pointed out that insulin degludec and liraglutide injection has a better hypoglycemic effect than basal insulin at the same or lower dose of insulin, and can reduce the risk of hypoglycemia, Avoid adverse reactions such as weight gain caused by insulin therapy. The reason why it can achieve the effect of “increasing efficiency and reducing side effects” is mainly due to the complementary mechanism of insulin and GLP-1 components, multi-target regulation, direct attack on the pathogenesis of type 2 diabetes, and effective control of blood sugar throughout the day once a day.
In order to further verify the efficacy and safety of the injection in the Chinese population, the DUALⅠ&Ⅱ China study was also carried out in my country. Low risk of hypoglycemia and weight benefit. In addition, it uses a pre-filled injection pen, once a day, which is not affected by meals, which not only reduces fasting blood sugar, but also covers blood sugar after meals throughout the day, providing patients with a simple and high-quality individualized sugar control solution.
The world’s first basal insulin GLP-1RA injection has been implemented in many provinces and cities across the country Drug availability
Written by: Nandu reporter Zeng Wenqiong
Intern: Xiao Tongdan
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