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Expert of this article: Zhao Jing, the Third Medical Center of the PLA General Hospital, attending physician Teacher
Review of this article: Li Jiehui, Deputy Chief Physician, Fuwai Hospital, Chinese Academy of Medical Sciences
< /p>Alzheimer’s, a disease that makes people feel sad. Memory loss, often confused, and even some patients can’t recognize their relatives… Many families suffer from it.
Gallery copyright image, reprint without authorization< span>Unfortunately, the early symptoms of Alzheimer’s are easily overlooked, so that the best time for treatment is missed. How long is the incubation period for Alzheimer’s? What are the early signs of the body? How to prevent it? The following will give you a detailed explanation.
What is Alzheimer’s?
Alzheimer’s disease, also known as Alzheimer’s disease (AD), is a progressive neurodegenerative disease with insidious onset. It mostly occurs in people over 65 years old, and the prevalence in women is higher than that in men. Some patients are younger than 65 years old, and it is called early-onset Alzheimer’s disease.
The etiology of the disease is complex, considering family history, history of head trauma, low education level, span>Bad lifestyle habits such as smoking and harmful drinking; related to underlying diseases such as cardiovascular and cerebrovascular diseases, hypertension, diabetes, and thyroid diseases.
Women more prone to Alzheimer’s?
The number of people with Alzheimer’s disease is increasing year by year, “China Alzheimer’s Disease Report 2021“ mentioned that the prevalence rate of Chinese women is 11.889/100,000, and the mortality rate is 30.8/100,000, The prevalence rate of women is about 2% of that of men. times.
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Researchers have found that women’s brains diffuse differently in the way tau, a protein that can damage nerve cells when tangled together. At the same time, studies have confirmed that FSH is also the pathogenic factor of this disease. Before and after menopause in women, the FSH content rises sharply, which binds to the homologous FSH receptor on neurons and activates the C/EBPβ/AEP pathway, resulting in the disease.
What is the incubation period for Alzheimer’s?
The disease progresses slowly, and it is often difficult to determine when it begins.The incubation period can range from months to years. of up to 20 years. Therefore, early detection and early treatment are the key.
Watch out for early signs of dementia!
Early symptoms are memory loss, forgetting about recent events, and decreased judgment ability.
If there is recent memory loss and cognitive decline, great attention should be paid to the possibility of suffering from this disease. For example, I don’t remember what happened just now, but I remember clearly what happened for a long time. Or there is a decline in life ability, mental and behavioral changes.
How can dementia be prevented?
Alzheimer’s disease is a complex multifactorial disease. According to epidemiological studies and related literature, my country has listed some controllable risk factors. Controlling high-risk factors can play a certain preventive role.
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Hypertension, diabetes, dyslipidemia etc.bothThe independent risk factors of Alzheimer’s disease, the specific mechanism is not clear, therefore, the control of basal blood pressure, blood sugar, blood lipids, can play a certain preventive role.
bad living habits, such as heavy smoking, Middle-aged people who drink harmfully can increase the risk of Alzheimer’s disease. Smoking can increase the production of free radicals, activate the oxidative stress response in the brain, and lead to pathological changes in the brain.It can increase the incidence of Alzheimer’s disease by 56%. Therefore, quitting smoking and limiting alcohol can also prevent AD.
Overweight, Obese: The prevalence of overweight and obese people is higher than that of normal people. Weight control has a certain preventive effect on Alzheimer’s disease.
traumatic brain injury, cerebrovascular disease: with Patients with stroke have twice the risk of developing Alzheimer’s disease than patients without stroke.
educational level was inversely associated with Alzheimer’s disease risk. Considering that it may be related to cognitive reserve, the prevalence of low-education population is higher than that of high-education population. Therefore, living to old age can also prevent Alzheimer’s disease.
High-risk factors such as depression, sleep disturbance, etc.also Causes of Alzheimer’s disease. Therefore, maintaining a good mood and effective sleep can also prevent Alzheimer’s disease.
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