The authoritative journal “Nature” has published a series of heavy hits, these foods will promote tumor metastasis!

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It is clear that the surgery has been removed and the anti-tumor drugs have been taken, but why does it still metastasize?

Many cancer patients have the above doubts, and metastasis is like a nightmare for cancer patients, lingering, according to , metastasis is a problem of great concern to all cancer patients.

Faced with metastases, everyone will always try their best to fight it, some people will choose combination therapy, some people will choose the efficacy of medication Better drugs, some people will strengthen exercise, improve immunity, these efforts will ultimately reduce the risk of tumor metastasis.

But the foods we frequently eat in our daily life “stab us” in the back and drag us back, making our efforts in vain flow.

Knock on the blackboard, Multiple studies have confirmed that some foods in life can increase the risk of tumor cell metastasis!

01

Antioxidantsare a class of substances that can protect the human body from free radical damage. Some studies have shown that antioxidants can lower blood pressure and benefit physical and mental health, but some studies have found that antioxidants can promote Metastasis of tumor cells.

Researchers from the University of Texas Children’s Research Institute found that tumor cells were able to recover from anti-inflammatory drugs compared to normal cells. Oxygenated foods to obtain more benefits, thereby accelerating the metastasis of tumor cells. In this study, researchers found that patients who received an antioxidant diet died faster than those who did not.

Although the specific study has not been validated in human trials, the leader of the study still suggests that cancer patients should not supplement their diets Lots of antioxidants[1].

There are many foods rich in antioxidants in our daily life, including various fruits, vegetables, etc. We don’t need to worry about eating these foods. Because it is a physical necessity.

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< p>And what really needs to worry about are various health products,such as multivitamins, vitamin A, vitamin E and vitamin C, etc., as well as anthocyanins, natural Astaxanthin, lutein, lycopene, beta-carotene, grape seeds, coenzyme Q, Ganoderma lucidum spore powder, etc., all health products that promote antioxidants are rich in antioxidants , far more than our body needs, and excessive intake of these increases the risk of tumor metastasis.

In conclusion, if not recommended by a doctor, generally No need to take various supplements.

Palm oil everywhere 02

palm oil due to its price Low temperature, good thermal stability, very common in various foods, such as instant noodles, bread, biscuits, French fries, fried chicken, cakes, etc.

Studies show that palmitic acid in palm oil significantly increases the aggressiveness and size of tumor metastases

strong>[2]. The researchers cultured human oral cancer cells with palmitic acid, oleic acid and linoleic acid, and then inoculated the tumor cells into mice, and found that the tumor cells cultured only with palmitic acid showed a clear tendency to metastasize.

And follow-up research also found that palm cells treated with palm oil will retain “memory” even if the palm oil revelations are subsequently isolated , still maintains high transfer activity. This shows that palm oil can promote tumor metastasis[2] without long-term use.

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Therefore, cancer patients should check the food ingredients list when shopping for some snacks , and avoid foods that contain palm oil. Generally, palm oil is mostly used in food processing, and is rarely used in daily household oil.

Peanuts known as the “fruit of longevity”03

In 2021, British researchers found that frequent consumption of peanuts in cancer patients may increase the risk of tumor spread[3] span>.

rich in asparagine Aloe04

Asparagine is a non-essential amino acid that can synthesize various proteins. It was originally discovered from aloe vera. By changing the diet of mice, the Cambridge Cancer Institute found that asparagine promotes the spread of tumor cells to other organs. The research has been published in the internationally renowned journal ” [5] on Nature.

Coincidentally, the research team from the United States also found that asparagine can enhance the activity of mTORC1 through a special pathway, and the latter can promote tumor Metastasis and growth, and this metastases-enhancing effect also works when tumor cell metabolism is inhibited.

However, the study also found a good phenomenon, that is, Metformin combined with a low asparagine diet can reduce Inhibit tumor growth and metastasis, improve survival time[6].

source: Camel sqResearch design

There are many foods rich in asparagine in daily life, such as aloe vera, dairy products, beef, etc. Food is mainly a variety of fruits and vegetables.

This article does not tell you not to eat anything, but that cancer patients should pay attention to a reasonable diet, such as meat, eggs, milk, vegetables, Both fruits and staple foods should be available, and a variety of types should be ensured, but quantitynot too much of a certain type of food, and balanced nutrition is more appropriate. Under the condition of not affecting your own nutritional needs, try to avoid or reduce these foods that can promote tumor metastasis.

In addition, be cautious about various health products, supplements, etc. stone yourself in the foot”.

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Responsible editor: Mijian Science & Technology< /span>

References

[1]Piskounova, E., Agathocleous, M., Murphy, M. et al. Oxidative stress inhibits distant metastasis by human melanoma cells. Nature 527, 186–191 (2015).

[2] Pascual, G., Domínguez, D., Elosúa-Bayes, M. et al. Dietary palmitic acid promotes a prometastatic memory via Schwann cells. Nature 599, 485–490 (2021).

[3]Qicheng Zhao, Carrie A. Duckworth, Weikun Wang, Xiuli Guo, Hannah Barrow, D.Mark Pritchard, Jonathan M. Rhodes, Lu-Gang Yu, Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galectin-3 to promote metastasis by interaction with cancer-associated MUC1, Carcinogenesis, Volume 35, Issue 12, December 2014, Pages 2815–2821,

[4 ]Wang, W., et al., Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endot Helial secretion of metastasis-promoting cytokines. Carcinogenesis, 2021. 42(8): p. 1079-1088.

[5]Knott, S., Wagenblast, E., Khan, S. et al. Asparagine bioavailability governs metastasis in a model of breast cancer. Nature 554, 378–381 (2018).

[6]Krall AS, Mullen PJ , Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, et al. Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell Metabolism.

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