Daily Business Daily News March 10 this year marks the 17th World Kidney Day. Yesterday morning, the Nephrology Branch of Zhejiang Medical Association joined hands with the Second Affiliated Hospital of Zhejiang University School of Medicine to hold a kidney day charity clinic. Twenty nephrology experts from major hospitals in the province gathered for consultation in the Binjiang Campus of the Second Hospital of Zhejiang University to answer questions and provide health guidance for the citizens who came to consult.
The theme of this year’s World Kidney Day is “Everyone Pays Attention to Kidney Health – I Love My Kidney, Knowledge Strengthens Kidney”. In fact, there is a general lack of knowledge about the prevention and treatment of kidney disease among the general public, and the occurrence or even aggravation of the disease still occurs from time to time.
Acute renal failure was actually caused by taking antipyretics
The Department of Nephrology of the Second Hospital of Zhejiang University once received a 65-year-old uncle. At the end of last year, he felt that his stomach was very bloated, but his urine output gradually decreased. After 3 months of treatment in various places, the effect is very small, and it is even severe enough that I can’t even pull a drop of urine.
In the Second Hospital of Zhejiang University, it was found that his serum creatinine value had exploded to 1718 (normal reference value <132), and he was initially diagnosed as acute renal failure. Ma Kunling, director of the Department of Nephrology, reviewed the medical records, analyzed the possible causes of acute renal failure, and finally decided to perform a renal biopsy.
The results showed that the renal tubules showed moderate to severe pathological changes, and the tubular epithelial cells had vacuolar degeneration, shedding, necrosis, and renal interstitial edema and inflammatory cell infiltration. Clearly, this was acute renal failure due to acute tubular necrosis, most likely drug-related.
It turned out that 3 months ago, my uncle took the antipyretic acetaminophen because of a cold, and 1 week later, he developed abdominal distension, oliguria, chest tightness, shortness of breath and other symptoms. These small pills are the “fuse” that causes acute renal failure.
After finding out the cause, the team from the Department of Nephrology of the Second Hospital of Zhejiang University formulated a corresponding treatment plan. On the basis of maintaining hemodialysis, glucocorticoid therapy was given. After being hospitalized for a period of time, the uncle’s urine output increased, the condition was significantly relieved, and he was released from hemodialysis. At the latest review, his serum creatinine had dropped to around 100, and other indicators had basically returned to normal.
It is important to be careful when taking medication, and self-assessment of renal function is very important
There is a saying that “drugs are poisonous”. Most of the drugs are metabolized by the kidneys, and the drug concentration is further accumulated after reaching the renal tubules. Many drugs have certain nephrotoxicity, which may induce acute interstitial nephritis and acute tubular necrosis. If you are a patient with chronic kidney disease, you need to be more cautious. Taking antibiotics, proprietary Chinese medicines, etc., you should first consult a specialist, and remember to follow the doctor’s advice.
According to the statistics released by the International Society of Nephrology and the International Federation of Kidney Funds, there are 500 million people in the world with different degrees of kidney damage, and millions of people suffer from chronic kidney disease every year. Vascular disease death. Professor Chen Jianghua, chairman of the Nephrology Branch of the Chinese Medical Association, said that chronic kidney disease has the highest fatality and disability rate among all chronic diseases, because it usually has no symptoms at the beginning and is often ignored. Therefore, it is particularly important to detect and prevent kidney disease as early as possible. Self-assessment of renal function can mainly refer to the following aspects:
●Changes in urine output: The daily urine output of healthy people is generally between 1000ml-2500ml, which varies due to changes in water intake. If the urine volume is less than 400ml, it is called oliguria in medicine, and less than 100ml is called anuria. If the urine does not increase significantly after increasing the water intake, or the oliguria or anuria continues, you should be vigilant at this time. .
●Observe the accompanying symptoms: such as swelling of the lower limbs and eyelids, fatigue, anorexia, nausea, chest tightness, palpitation, dizziness, increased blood pressure, chest tightness during sleep, etc. The above changes may be related to the rapid development of renal failure. progress.
●Pay attention to the results of physical examinations: simple examinations can help to clarify the renal function, such as blood routine, urine routine, renal function electrolytes, urinary B-ultrasound, and serum creatinine, which should be paid special attention.