內容目錄
“The baby is only 4 years old, but aplastic anemia has been diagnosed! The sky is falling!”
“Shen Yujun, how can you get aplastic aplastic disease if you are doing well? Anemia?”
How does aplastic anemia come about? What are the triggering factors?
The superficial phenomenon is inextricably linked, but there is only one truth behind it.
“Etiology of Aplastic Anemia”, let’s go!
What is aplastic anemia? To sum up in one sentence, hematopoietic stem cells and blood cells are malfunctioning.
Simple understanding, hematopoietic stem cellsgenerated Blood cellseithernot enough, justPoor quality.
Why is the ability of hematopoietic stem cells to generate blood cells malfunctioning?
Deep Reader regrets to tell everyone that in today’s world, no one can tell exactly what happened to the hematopoietic stem cells.
Is the number of hematopoietic stem cells decreasing? Or did something go wrong in the process of making blood cells? Or give birth to malformed blood cells? All of this is a mystery.
Deep reading Jun found that these three factors may lead to aplastic anemia.
genetic
aplastic anemiaRelated togene, with a certain genetic predisposition strong>.
becausegenescontainedinheritance Information is different, some people are born with hematopoietic stem cell hematopoietic functionweak,Bone marrowcannot produce enoughblood cells, which is /span>Congenital aplastic anemia.
abnormal hematopoietic microenvironment p>
Hematopoietic stem cells undergo proliferation, differentiationtransformation intoblood cells< /span>Baby.
Blood cellsYour baby grows and develops into mature blood cells.
Mature blood cells go throughsinusesto become new blood cells.
All factors involved in the above links constitute hematopoietic stem cell hematopoietic microenvironment .
Abnormality in any of these links will lead tohematopoietic dysfunction.
For example, the growth factors secreted by stromal cells are not strongineffective, and hematopoietic stem cells cannot at all. Complete differentiation.
For exampleswelling of the sinusoids, blocking the passage of mature blood cells into the bloodstream.
Read Jun Xiao Summary:The abnormal hematopoietic microenvironment may lead to aplastic anemia.
immune factors
Some patients with aplastic anemia have a problem in the bodyimmune system,< span>T cells are crazy, they don’t take the eradication of pathogens as their mission, but they can target bone marrowhematopoietic stem cells in >.
Hematopoietic stem cells have been attacked with countless casualties, and hematopoietic function is almost destroyed. Yes, aplastic anemia.
What factors can induce aplastic anemia?
Radiation
Radiation may damageHematopoietic stem cells, affectinghematopoietic function, resulting in aplastic anemia.
Prevention of aplastic anemia starts with radiation protection.
virus
infectionhepatitis virus, Cytomegalovirus, dengue fever virus, etc., may cause aplastic anemia.
After these kinds of damn viruses are infectedbone marrow hematopoietic stem cells, there may be Causes hematopoietic stem cell damage, affecting its hematopoietic function, causing aplastic anemia.
Prevention of aplastic anemia starts with prevention of viral infections.
drugs
< p>Some drugs may damagehematopoietic stem cells in the bone marrow, causinghematopoietic function Barriers. For example, some anti-tumor drugs, chloramphenicol antibiotics, sulfonamides, etc.
Taking antitumor drugs as an example, tumor cellsand < strong>Hematopoietic stem cellsall belong to the human body vigorously dividing cells, some of which are resistant to Tumor drugs target these vigorously dividing cells, and may accidentally injure hematopoietic cells in the process Stem cells, causing abnormal hematopoiesis.
Prevention of aplastic anemia starts fromaccording to the doctor’s advice and using scientific medicine.
disease
< p>Some diseases may cause aplastic anemia.
systemic lupus erythematosus, rheumatoid arthritisand other autoimmune diseases in which the immune system attacks itself of good cells.
In case of bad luck,immune systemstarts attacking itselfBone marrow hematopoietic stem cells, it is possibleGet aplastic anemia.
Prevention of aplastic anemia begins with scientific treatment of immune system diseases.
“Shen Du Jun, what should be checked for aplastic anemia? Treatment?”
For those dry goods about “Aplastic Anemia Investigation and Treatment”, Shen Du Jun has already prepared it.
In the next episode, Deep Reader will work harder, waiting for you, see you soon!
Follow “Deep Reading Video”, remember to like and forward! Chimi!
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