Study shows: China’s new crown inactivated vaccine can effectively protect against Omicron

People’s Daily Health Client Reporter Zhao Weide

The reporter learned from the New Coronary Pneumonia Prediction Group of Lanzhou University on March 8 that the Preprints preprint platform released the team’s research article on the effective protection of the new crown inactivated vaccine against the large-scale outbreak of the Omicron epidemic. . Research shows that China’s new crown inactivated vaccine has effectively reduced the outbreak scale of the Omicron epidemic, and the broad-spectrum advantages of inactivated vaccines can effectively deal with virus mutation.

Lanzhou University’s New Coronary Pneumonia Epidemic Prediction Team told a reporter from the People’s Daily health client that there has not been a major outbreak in countries where inactivated vaccines are the mainstay. One of the keys to the Micron virus outbreak. Previously, the cumulative confirmed cases of Omikoron outbreaks in Tianjin (1.8), Anyang City, Henan (1.8), and Hangzhou City, Zhejiang (1.26) were 361, 463, and 114, respectively. The surge has decreased significantly.

On January 28, “Nature” published a research article led by researcher Wang Xiangxi from the Institute of Biophysics, Chinese Academy of Sciences. The research results show that the booster injection of the new crown inactivated vaccine can improve the B-cell immune memory achieves protection against severe infection by Omicron mutant strains. Earlier real-world data in Brazil, Chile and other countries showed that the severe protection efficiency of two doses of inactivated vaccine against Delta mutants exceeded 80%.

In addition, the above study shows that after three doses of vaccine immunization, some memory B lymphocytes carry broad-spectrum neutralizing antibodies, and when the human body is infected with the Omicron variant, This part of the memory B cells will be specifically activated and proliferated, producing a large number of plasma cells that can secrete highly effective neutralizing antibodies, thus achieving severe protection against the Omicron variant.

At the same time, in the face of the next stage of epidemic prevention and control, Zhang Boli, an academician of the Chinese Academy of Engineering, told a reporter from the People’s Daily Health Client that the approval of vaccines designed to deal with the Omicron strain should also be accelerated. , to speed up the relevant approval procedures, and to carry out vaccine clinical trials in China with reference to the test results of China’s Omicron vaccine in foreign countries. It can be used as a booster for sequential immunization for general vaccination, so that the whole population can passively form a herd immunity barrier against Omicron virus.

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