Study: Protection from hospitalization with third dose of Pfizer’s COVID-19 vaccine wanes after 3 months

A study published April 22, 2022 in The Lancet Respiratory Medicine shows that booster doses of Pfizer’s COVID-19 vaccine are effective against COVID-19 in the first few months The delta and omicron variants of delta and omicron provide strong protection from hospital admissions and emergency department visits, approximately 80% to 90%. However, this protection against Omicron can get worse over time — even after the third shot.

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Sara Y. Tartof, Ph.D., lead author of the study, said: “Pfizer BioNTech’s COVID-19 booster dose significantly improved protection against Omicron, although this protection appears to be Protection against emergency room visits and even hospitalizations weakened after 3 months. The weakening trend for delta-related outcomes was generally similar to that of Omicron, but the effectiveness at each time point was greater than that of Omicron See it higher.”

The researchers looked at 11,123 hospital admissions and emergency department visits in this study, who were not hospitalized for acute respiratory infections. The researchers looked at patient records at Kaiser Permanente Southern California between Dec. 1, 2021, and Feb. 6, 2022, when both the Delta and Omicron variants were circulating in the population.

Pfizer’s COVID-19 vaccine is known to be 41% effective against Omicron and 9 months for emergency room visits after 2 doses 31%;

After 3 doses, 85% effectiveness against Omicron-related hospitalizations at less than 3 months, but at 3 months or more It dropped to 55%;

For emergency room visits that did not result in hospitalization, the 3-dose vaccine was 77% effective against Omicron in less than 3 months, but at 3 months or more Over the long term it dropped to 53%.

Tartof noted that while Pfizer’s COVID-19 level of protection against Omicron was much higher after 3 doses than after 2 doses, it was lower than protection against Delta or other COVID-19 -19 strain. To maintain high levels of protection, additional doses of the new COVID-19 vaccine may be required to ward off subsequent outbreaks of COVID-19 caused by Omicron or future variants with similar potential.

Source: cnBeta.COM