Amoxicillin and cephalosporin, two anti-inflammatory drugs, have a very wide range of clinical applications. I believe everyone is familiar with them, but most people do not know what the difference is between them. , Which one should be more appropriate when the disease appears? Let’s discuss it with you today.
First of all, let’s talk about amoxicillin. Amoxicillin is a semi-synthetic broad-spectrum penicillin that can kill a variety of bacteria, but not all types of bacteria. It can be used for any infection caused by hemolytic streptococcus, streptococcus pneumoniae, staphylococcus, enterococcus faecalis and other aerobic gram-positive bacteria, as well as Salmonella, Escherichia coli, Haemophilus influenzae, Neisseria gonorrhoeae Aerobic Gram-negative bacteria such as bacteria and Helicobacter pylori and other pathogens have good antibacterial activity.
Indications include respiratory tract infections caused by sensitive bacteria, such as pharyngitis, tonsillitis, bronchitis, pneumonia, as well as urinary tract infections, bile ducts, skin and soft tissue infections.
It should be noted that a very small number of people may experience laryngeal edema and anaphylactic shock after taking amoxicillin, so be sure to do a penicillin skin test before taking it. It can only be used if the skin test is negative.
Next, let’s talk about cephalosporins. There are many kinds of cephalosporins. According to the stability of antibacterial spectrum and nephrotoxicity, cephalosporins are divided into 5 generations. Commonly used are first-generation, second-generation and third-generation.
First-generation cephalosporins include cephalexin, cefradine, cefadroxil, cefazolin and other drugs, which are effective against Staphylococcus aureus. , Streptococcus (except Enterococcus) and other gram-positive bacteria have strong activity, better than the second and third generation cephalosporins, except for Enterococcus.
Second-generation cephalosporins include cefuroxime, cefaclor, cefamandole, etc., which are slightly less effective on gram-positive bacteria than first-generation cephalosporins, but are less effective on gram-negative bacteria. The effect is stronger than the first generation cephalosporin, the antibacterial spectrum is wider, and the nephrotoxicity is smaller than the first generation.
The third-generation cephalosporins include cefixime, ceftriaxone, cefoperazone, etc. It has significant antibacterial activity against gram-negative bacteria, and is less nephrotoxic than first- and second-generation cephalosporins. For the 4th and 5th generation cephalosporins, we basically can’t see them, and they are only allowed to be used in special circumstances.
Cephalosporins can be distributed in various parts of the body, such as skin and soft tissue infections, urogenital and respiratory infections, etc. As long as the pathogenic bacteria are sensitive to cephalosporins, they can be used under the guidance of a doctor . In addition, everyone must pay attention to the fact that cephalosporins will affect the metabolism of alcohol in the body, causing acetaldehyde to accumulate in the body, resulting in disulfiram-like reactions, flushing, difficulty breathing, and even cardiac arrest. It is strictly forbidden to drink alcohol while taking cephalosporins. of.
To sum up: Knowing some professional knowledge of amoxicillin and cephalosporin can better help us choose targeted antibacterial drugs, rational use of clinical antibiotics and improve Efficacy is important. Whether cephalosporin or amoxicillin, must be selected under the guidance of a doctor. Before taking amoxicillin, a penicillin skin test must be done. It can only be used if the skin test is negative. Alcohol consumption should be strictly prohibited during the use of cephalosporins. In addition, amoxicillin and cephalosporin are strictly prohibited for external use.