There are more than 7,000 rare diseases known worldwide, of which only a tiny fraction are currently curable. However, it is the very small number of rare diseases that can be treated. The annual treatment cost is also astronomical for ordinary families, ranging from hundreds of thousands a year to one or two million. February 28, 2022 is the 15th International Rare Disease Day. Experts call for attention to rare diseases so that patients with rare diseases can have a wonderful life.