Benefits of getting a flu shot may far exceed expectations
According to the “Report of the Third National Death Cause Review and Sampling Survey”, cerebrovascular disease has now jumped to the top of the national cause of death, and stroke is the disease with the highest disability rate of a single disease1 .
What many people don’t know is that the flu is also a high risk factor for stroke. A seemingly ordinary flu may be the trigger for a stroke. Therefore, preventing the flu is equivalent to preventing stroke at the same time.
Influenza virus infection may be the trigger for stroke,
May also worsen stroke outcomes
Influenza virus infection can cause stroke. A self-controlled case series in Scotland including 762 new strokes and 1227 new myocardial infarctions after laboratory-confirmed bacterial or viral infection between 1 January 2004 and 31 December 2014, aimed to quantify Association between laboratory-confirmed respiratory bacterial or viral infections and new stroke and myocardial infarction.
The results showed that the risk of the first stroke within 1-3 days after influenza infection increased by 7.82 times (95%CI: 1.07-56.9, P=0.042)2.
Influenza virus infection increases risk of first stroke2
In a recent US study, influenza-like illness hospitalizations were significantly associated with increased odds of ischemic stroke. This study conducted a case-crossover analysis of the 2012-2014 New York Statewide Planning and Research Collaborative System to estimate the odds of ischemic stroke and myocardial infarction after influenza-like illness. The results showed that hospitalization for influenza-like illness in the first 15 days increased the incidence of ischemic stroke by 39% (OR=1.39; 95% CI: 1.09-1.77; P69% strong>(OR=1.69; 95%CI: 1.56-1.83; P3.
Influenza may also worsen stroke outcomes. In a basic study, mice were infected with HIN1 virus and occluded the middle cerebral artery to induce ischemic stroke. The infarct volume and intracerebral hemorrhage were measured histologically to evaluate the effect of H1N1 infection on ischemic stroke in mice. effect of the ending. The results showed: The infarct volume of stroke mice increased after H1N1 infection4.
Benefits of getting a flu shot may far exceed expectations
Getting the flu vaccine reduces the risk of new strokes, recurrent strokes, or any stroke. A meta-analysis of 11 studies investigating the effect of influenza vaccination on the risk of subsequent stroke was conducted to determine whether influenza vaccination prevents stroke. The results showed that influenza vaccination significantly reduced the risk of stroke (OR=0.82; 95% CI: 0.75-0.91; P. Four studies showed that influenza vaccination strong>Reduce the risk of new stroke(OR=0.81; 95%CI: 0.78-0.85), 3 studies showed that influenza vaccination reduced the risk of recurrent stroke< /strong>(OR=0.75; 95%CI: 0.70-1.01), of which 7 studies showed that influenza vaccination reduces the risk of any stroke(OR =0.73; 95%CI: 0.59-0.90)5.
Influenza vaccine reduces risk of stroke5
Influenza vaccination reduces the risk of hospitalization for ischemic stroke, and the risk of hospitalization for ischemic stroke decreases significantly with increasing number of influenza vaccinations. A population-based case-control study in Taiwan including 520 hospitalized patients over 65 years of age with ischemic stroke and 2600 matched controls during the 2006-2009 influenza season was designed to investigate the effect of influenza vaccination on ischemic stroke. Effects of stroke hospitalization risk. Results: Influenza vaccination reduces the risk of hospitalization for ischemic stroke in older adults, and annual vaccination provides greater protection6.
Influenza Vaccination Reduces Risk of Ischemic Stroke Hospitalization6
The flu vaccine also significantly reduces the risk of death from stroke. A study of 102,698 elderly people over the age of 65, divided into flu vaccine groups (n=35637) and unvaccinated groups (n=67061), was designed to investigate whether influenza vaccines are effective in reducing major cause of death risk. The results showed that influenza vaccination could significantly reduce the risk of all-cause mortality (HR=0.56; 95%CI: 0.52-0.60, P7.
Influenza vaccination reduces risk of death from stroke7
Guideline Recommendation: Annual Influenza Vaccination
Can effectively reduce stroke risk in stroke patients
In summary, getting the flu vaccine can not only prevent the flu, but also effectively reduce the risk of stroke. It really kills two birds with one stone! Did you get the flu shot this year? If you haven’t been called yet, please go to the nearest community health service center to make an appointment and get vaccinated!
References:
1. National Health Commission of the People’s Republic of China. Guidelines for Chinese Stroke Prevention and Treatment (2021 Edition).
2. Charlotte Warren-Gash, et al. Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland. Eur Respir J. 2018 Mar 29;51(3):1701794.
3. Erin R Kulick, et al. Risk of stroke and myocardial infarction after influenza-like illness in New York State. BMC Public Health. 2021 May 5;21(1):864.
4. Sajjad Muhammad, et al. Influenza virus infection aggravates stroke outcome. Stroke. 2011 Mar;42(3):783-91.
5. Kyu Rae Lee, et al. Effect of Influenza Vaccination on Risk of Stroke: A Systematic Review and Meta-Analysis. Neuroepidemiology. 2017;48(3-4):103-110 .
6. Hui-Chen Lin, et al. Association of influenza vaccination and reduced risk of stroke hospitalization among the elderly: a population-based case-control study. Int J Environ Res Public Health. 2014 Apr 2;11(4):3639-49.
7. Chong-Shan Wang, et al. Impact of influenza vaccination on major cause-specific mortality. Vaccine. 2007 Jan 26;25(7):1196-203.
8. James F Meschia, et al. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Dec;45(12 ):3754-832.
*This information is for medical and scientific reference only, and does not constitute a recommendation or promotion of any drug or treatment plan. The information contained in this article should not be used as a substitute for medical advice from a healthcare professional.
Approval Number: MAT-CN-2202147 Expiration Date: 2/22/2023
*The copyright of this article belongs to the original author, if you need to reprint, please contact the original author for authorization