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Source: Center for Drug Evaluation< /p>
Recently
#ibuprofen does not answer urgent orders# topic rushed to the hot search
< span>Causing heated discussions among netizens!
This topic originated from a post by a netizen
the netizen said /span>
My stomach still hurts 1 hour after taking ibuprofen!
A hot comment in the comment areaa bit funny
ibuprofen
as a pain reliever
For netizens who suffer from frequent headaches, toothaches, and dysmenorrhea,
is not unfamiliar
but only if it starts to hurt. Netizens who took medicine
dysmenorrhea found
>Netizens who have a cold or a toothache found that
This way
Only for dysmenorrhea patients
“Ibuprofen does not accept urgent orders”
Let’s learn more “Why”
How does ibuprofen relieve pain?
There are pain-causing substances in the body called prostaglandins.
ibuprofen is by inhibiting the synthesis of prostaglandinsto exert antipyretic, anti-inflammatory and analgesic effects.
Ibuprofen has nothing to do with prostaglandins that have been synthesized.
As soon as they see the word “prostaglandin”, many people immediately think of the prostate, an accessory gland of the male reproductive system, and then think that “prostaglandin” is produced by the prostate gland. secreted.
This is not the case.
In 1930, scientists discovered that there is an active substance in the semen of humans, monkeys and sheep that can excite smooth muscle and lower blood pressure span>. At the time, it was thought that it might be secreted by the prostate, and it was named prostaglandin.
But later studies found that a variety of tissue cells in the body can secrete prostaglandins, and women also contain prostaglandins.
Mechanisms of Dysmenorrhea
Dysmenorrhea is one of the most common gynecological symptoms worldwide. About 80% of women have varying degrees of dysmenorrhea, of which about 3/4 affect work.
Dymenorrhea can be divided into two categories, one is primary dysmenorrhea without obvious organic lesions in reproductive organs< span>, a type of dysmenorrhea caused by definite diseases of the reproductive organs is called secondary dysmenorrhea.
Primary dysmenorrhea is mainly related to excessive synthesis of prostaglandin (PG) in the endometrium during menstruation.
Prostaglandin (PG) is synthesized by the endometrium, but its receptor is located in the myometrium. PG can cause smooth muscle contraction and even spasm, and at the same time lead to increased intrauterine pressure, decreased uterine blood flow, uterine ischemia and hypoxia, and dysmenorrhea.
Medical treatment of primary dysmenorrhea
ibuprofen< span>Non-steroidal anti-inflammatory drugs such as NSAIDs are the first-line treatment drugs for primary dysmenorrhea.
If the symptoms of dysmenorrhea are still not significantly improved after using NSAIDs, it is recommended to exclude secondary dysmenorrhea.
Timing of dosing of ibuprofen
ibuprofen inhibits only prostaglandins It has no effect on the synthesized prostaglandins, so it needs to be used before dysmenorrhea.
Ibuprofen Dosage:
In the estimated Start taking 24~48 hours before menstruation, 200~400mg each time, 3~4 times a day, and last until 1~2 days after menstruation starts.
These precautions should be taken when taking ibuprofen
It is best not to take long-term or Use ibuprofen in large quantities for no more than 5 days for pain relief and no more than 3 days for fever relief.
Drinking alcohol while taking this medication may increase the risk of gastrointestinal bleeding and serious cardiovascular side effectsPlease avoid alcohol or alcoholic beverages.
Please do not take other medicines containing antipyretic and analgesic ingredients at the same time, especially note that some compound cold medicines may contain non-steroidal anti-inflammatory drugs pharmaceutical ingredients.
Ibuprofen may induce or exacerbate high blood pressure, and it is recommended that you monitor blood pressure closely during use.
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