Hunan CDC: CanSino new crown vaccine can be selected for “mixed fight” booster shots

內容目錄

Recently, there have been new confirmed cases of the new crown in many provinces, and many of them are the transmission chain of the Omicron variant. With the approval of the Joint Prevention and Control Mechanism of the State Council, the National Health Commission has begun to deploy sequential vaccination of the new crown vaccine.

The reporter learned from the Hunan Provincial Disease Control and Prevention that the Hunan new crown vaccine sequential booster immunization has also been officially launched. This means that the new crown vaccine can be “mixed”. Tianjin CanSino Bio-recombinant new crown vaccine (type 5 adenovirus vector) Keweisha has also become the first adenovirus vector new crown vaccine approved for sequential booster immunization in China.

The third shot is vaccinated with the same technique as the first two shots, which is called booster vaccination. If the first two shots are inactivated vaccines, and the third shot is inoculated with other techniques such as adenovirus vector vaccines, it is called sequential vaccination. The booster sequential vaccination launched this time is also called “heterologous vaccination” (commonly known as “mixed fight”), that is, the new crown vaccine using different technical routes for basic immunization and booster immunization, which is equivalent to giving the body double doses from different technical routes. protective barrier.

According to the information released by the National Health and Health Commission, all people who have been vaccinated with the inactivated vaccine of Sinopharm Zhongsheng Beijing Company, Wuhan Company, Beijing Kexing Company, and the adenovirus vector vaccine of Tianjin CanSino Company have been vaccinated for 6 months. The target population over 18 years old can receive one dose of homologous booster immunization. After the implementation of the sequential immunization strategy, the target population who has completed the whole process of inoculating the above three inactivated vaccines can also choose recombinant protein vaccine or CanSino’s adenovirus vector vaccine for sequential immunization. For the target population, one of homologous booster immunization and sequential immunization can be selected.

That is to say, people who have been vaccinated with two doses of inactivated vaccine before have a new option for the third dose – they can choose adenovirus Vaccines from other processes such as vector vaccines are vaccinated. In terms of effectiveness, after two doses of inactivated vaccine, one dose of CanSino adenovirus vector new crown vaccine is given as a boost. Research data show that the antibody level is 5 times higher than that of inactivated vaccine homologous booster immunization, and 7 times higher than that of recombinant protein vaccine sequential booster. In addition, for the Omicron variant, the research data shows that the level of neutralizing antibodies in the sequential enhancement of the CanSino adenovirus vector new crown vaccine is 3 times that of the recombinant protein vaccine, and 6 times that of the homologous inactivated vaccine. CanSino adenovirus vector vaccine boosting effect is excellent.

The above studies show that the use of CanSino adenovirus vector 2019-nCoV vaccine sequential boosting has good safety and immunogenicity. For the existing new crown mutants, sequential vaccination of CanSino adenovirus vector vaccine is effective, and its overall protection rate and severe protection rate are maintained at a high level.

Disease control experts said that to prevent the disease, it is also necessary to prevent the spread, and at the same time, it must be able to resist various mutant strains. Therefore, it is necessary to speed up the iteration of vaccines, so that protective and safe vaccines can be put into use quickly, in order to grasp the initiative in the fight against the epidemic.

Xia Sheng, reporter of Xiaoxiang Morning News

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