Hu Dayi: Talking about the problems in the use of blood pressure lowering drugs (Part 1)

1. When should I take the medicine?

Many patients are accustomed to taking their medicines in the morning after waking up, based on frequent physician recommendations or past guidelines. However, many patients have a “morning peak” of blood pressure in the early morning, that is, a blood pressure peak occurs at 5 to 6 in the morning. Some patients also have high blood pressure at night. Therefore, these patients should take antihypertensive drugs after dinner and before going to bed.

2. Pay attention, don’t overdo it.

In recent years, experts have said every day, and guidelines have repeatedly said that to effectively prevent stroke, it is necessary to maintain 24 Blood pressure dropped steadily. This is theoretically correct. But in practice something went wrong. Some elderly people, after retirement, attach great importance to health care, and measure blood pressure frequently every day, even every one to two hours, and even get up at night to measure. When blood pressure fluctuates, I get nervous. Ask your doctor, and some will prescribe a quick-acting blood pressure-lowering drug, such as captopril. Some old couples have high blood pressure, and they measure each other’s blood pressure every hour. This is a “blood pressure anxiety disorder”. There are more and more types of antihypertensive drugs, and the doses are getting larger and larger. Because of the use of 3-5 kinds of antihypertensive drugs, the blood pressure is still fluctuating, so I was misled and overtreated in the previous period, and received renal artery sympathetic nerve radiofrequency. Ablation, postoperative blood pressure fluctuations remained.

I have persuaded many elderly hypertensive patients to change their self-monitoring blood pressure behavior. “Pay attention, don’t overdo it!” Not only did the blood pressure stabilize quickly, but the types and doses of blood pressure-lowering drugs needed were greatly reduced. If you want to know whether your blood pressure drops steadily for 24 hours, you can do a 24-hour ambulatory blood pressure monitoring if necessary, instead of measuring your blood pressure too frequently at home.

3, pay attention, don’t overdo it. What should I do if the low pressure (diastolic blood pressure) is high and the pulse pressure is small?

This condition is more common in young and middle-aged hypertensive patients. The most frequently asked question when they come to the hospital outpatient clinic is “Which blood pressure lowering drug is more effective in lowering blood pressure?” In fact, all blood pressure lowering drugs both lower blood pressure and lower blood pressure. There is no single drug that is more effective in lowering blood pressure than which drug. These patients are often obese, rarely exercise, eat too much, some drink a lot, sleep snoring, stay up late for excessive entertainment, etc. The key is to keep your mouth shut and spread your legs. Eat 80% full, walk 10,000 steps a day, limit alcohol, control your weight, and ensure adequate sleep. In order to better exert the blood pressure lowering effect of blood pressure lowering drugs, it may even be possible to reduce and stop the drugs, open the pulse pressure, and keep the blood pressure normal.

4, isolated systolic blood pressure.

High blood pressure (systolic blood pressure), low pressure (diastolic blood pressure) not high, even low, high pulse pressure , more common in elderly hypertensive patients. Antihypertensive drugs are not drugs that lower systolic blood pressure and do not affect diastolic blood pressure. However, the magnitude of blood pressure reduction by antihypertensive drugs depends on the degree of basal blood pressure increase before the drug. The higher the blood pressure before the drug, the more obvious the blood pressure drop of the antihypertensive drug. Therefore, for the elderly who simply increase systolic blood pressure, antihypertensive drugs significantly reduce systolic blood pressure and have little or little effect on diastolic blood pressure. Increased systolic blood pressure is the greatest risk for stroke. Don’t be afraid to control systolic blood pressure with antihypertensive drugs because of excessive concern about the drop in diastolic blood pressure. The systolic blood pressure of the elderly (over 80 years old) can be reduced to below 150mmHg, but if it is reduced to below 140mmHg, it will feel good and better.