The opening ceremony of the 2021 China Oncology Congress (2021CCO) was held in Zhengzhou
Top News·Henan Commercial Daily reporter Xiong Zhuotian Wang Yinping
At 9:00 am on April 16th, the opening ceremony of the 2021 China Oncology Congress (2021CCO) was held in Zhengzhou. At the meeting, the “China Integrated Tumor Diagnosis and Treatment Guidelines (CACA Guidelines)” was officially released, and 7 celebrities gathered in the cloud to give keynote speeches.
It is reported that the keynote report, as one of the most important academic feasts of the CCO conference every year, has always attracted much attention. Since 2018, a keynote report selection system has been established. Each session of the keynote report is born by institutional recommendation, repeated selection, and mutual evaluation of experts. It shows the latest concepts, latest strategies, latest technologies and latest achievements in the field of oncology in my country.
The top news Henan Business Daily reporter learned that before the current CCO conference, the CCO keynote report selection meeting jointly organized by Ganqing, Qingning and Ningxia anti-cancer associations was held in Xining. Witnessed by more than 1,000 delegates, after two rounds of review and intense competition, seven experts were successfully selected for the keynote report of the 2021 CCO Conference.
Among them, Gao Quanli, member of the Cancer Biotherapy Committee of the China Anti-Cancer Association and director of the Immunotherapy Department of Henan Cancer Hospital, shared the theme: “Tumor Immune Cell Therapy, Treat the Eve with Kindness at Dawn”.
Gao Quanli said that immunotherapy is one of the frontier hotspots in current tumor treatment research, and breakthrough effects have been achieved in some hematological tumors. As of April 16, 2021, there were 2,073 R&D pipelines of immune cell therapy drugs in the world, an increase of 572 over the same period in 2020, a growth rate of 38%. There are many types of immune cell therapy with different mechanisms of action, mainly including CAR-T, TIL, TCR-T, NK and DC and other cell therapies, especially CAR-T cell therapy has achieved outstanding results in the treatment of hematological tumors .
So, what exactly is immunotherapy? What is the difference between chemotherapy and radiotherapy?
“Chemotherapy, surgery, radiotherapy, and targeted therapy mainly target cancer cells, such as target Orientation therapy is to use ‘missiles’ to kill cancer cells precisely and directly, while immunotherapy generally does not work directly, but kills tumor cells by mobilizing immune cells.” Gao Quanli said, for example, CAR-T cell therapy is This is done through the following steps: T cells are extracted from the patient–engineered into CAR-T cells using genetic engineering techniques–largely expanded CAR-T cells–infused back into the patient for treatment.
The principle is probably that T cells are a kind of immune cells in the human body and one of the natural defense lines of the human body against pathogenic invasion. Natural T cells are “ordinary troops”, while CAR-T is equivalent to “special forces”.
When encountering specific tumor cells, the CAR-T cells injected into the patient will be activated, proliferate in large quantities, and kill off the disease, attacking and killing tumor cells such as diseased leukocytes to achieve treatment. Effect.
Gao Quanli mentioned that immunotherapy is a relatively new subject and a new method of tumor treatment developed in the past ten years. At present, most tumors are in the process of treatment. It will be applied to immunotherapy, but it also has certain shortcomings, such as low efficiency, and even some patients will have more serious side effects. “However, such a brand-new subject has a very good development prospect. In the future, there will be more new immunotherapy applications in tumor treatment, and tumor patients will benefit more!”
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