After Laba is the New Year, family and friends gather for dinner, and it is inevitable to change the cup. And if you or your family and friends happen to be taking medicine, then you should pay attention: Drugs and alcohol are not worth it at all. Especially if you are taking the following medicines, you must not drink alcohol!
1.cephalosporins< /span>
< span>Most cephalosporins contain a tetrazolium group similar to disulfiram in chemical structure. Drinking alcohol before and after taking the drug may cause a disulfiram-like reaction. Disulfiram-like reaction refers to the fact that certain drugs have a similar chemical structure to disulfiram.If you drink alcohol after taking the drug, you may experience facial flushing, conjunctival hyperemia, blurred vision, and blood vessels in the head and neck. Severe throbbing or throbbing headache, dizziness, nausea, vomiting, difficulty breathing, convulsions, and even death. Once a disulfiram-like reaction occurs, the drug and alcohol-containing products should be discontinued in time. The mild cases can be relieved by themselves, and the severe cases need to be sent to the hospital for oxygen inhalation and symptomatic treatment.
Special reminder, Do not use cephalosporins within 3 days after drinking alcohol. Do not drink alcohol within 7 days of taking the medicine, and prohibit alcohol-containing medicines and foods, such as eating wine chocolate, taking Huoxiangzhengqi water, using injections containing ethanol as excipients, and using alcohol to treat skin.
In addition, nitroimidazoles such as metronidazole, tinidazole and ethanol may also have a disulfiram-like reaction and should be used separately.
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2.acetaminophen tablets
acetaminophen tablets It is the ingredient used in most cold medicines to reduce fever, and is also commonly used to relieve mild to moderate pain (such as joint pain, migraines, etc.). Studies have shown that alcohol consumption may increase acetaminophen hepatotoxicity.
3.antihypertensive drugs
Excessive drinking can dilate blood vessels, inhibit sympathetic nerves and vascular motor centers, and reduce myocardial contractility. If you take antihypertensive drugs after drinking, the small blood vessels will be more dilated, blood volume will be further reduced, blood pressure will drop sharply, and orthostatic hypotension or syncope will easily occur.
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4.aspirin
Pharmacokinetics between aspirin and ethanol and certain pharmacodynamic interactions. Ethanol intake of any concentration will increase the irritation to the digestive tract, easily cause gastric mucosal lesions or ulcer recurrence, andincrease the risk of upper gastrointestinal bleeding associated with aspirin.
5 .Sedative Hypnotics
After sedative-hypnotic drugs are combined with ethanol, the degree of inhibition on the central It is related to the type of drug, dosage, and alcohol consumption. Increased drowsiness, decreased response sensitivity, distraction, poor coordination, and even death in severe cases.
6 .Anti-epileptic drugs
Ethanol can affect the metabolism of some antiepileptic drugs, thereby affecting their efficacy. Also, drinking alcohol itself can cause seizures. Therefore, it is not suitable for people with epilepsy to drink alcohol.
7 .Hypoglycemics
Drinking alcohol while taking sulfonylureas can cause severe hypoglycemia or irreversible neurological disease. can also cause a “disulfiram-like reaction” because ethanol can lower blood sugar by blocking the conversion of glycerol, lactic acid, and certain amino acids into sugars.
In conclusion, ethanol can alter the response of many drugs, and heavy drinking can affect the biotransformation of many drugs. You should read the instructions carefully during taking the medicine, and promptly inform the doctor of your recent drinking history when you visit the doctor. During the use of the above drugs, alcohol should be avoided to avoid serious adverse reactions.
Source: Healthy China
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