On March 16, the first autologous hematopoietic stem cell transplant patient in Gansu Provincial Hospital of Traditional Chinese Medicine was successfully released from the warehouse. This is also the first successful case of hematopoietic stem cell transplantation in the Northwest Traditional Chinese Medicine Hospital, filling the gap of hematopoietic stem cell transplantation in the Northwest Traditional Chinese Medicine Hospital.
A group photo of the patient and medical staff
The patient Ms. Yang was diagnosed with “primary center” in 2020. Diffuse large B-cell lymphoma of the system”, and achieved remission after regular chemotherapy. Due to the poor recovery of the disease, the patient and his family decided to undergo autologous hematopoietic stem cell transplantation in January 2022 and went to the Department of Traditional Chinese Medicine in the province. The starter started on January 12, and the peripheral hematopoietic stem cells were collected on January 24. A total of 185ml of up-to-standard stem cells were collected. Ms. Yang officially entered the warehouse on February 21, and underwent pre-transplantation pretreatment, followed by hematopoietic stem cell infusion, and the infusion process went smoothly. After the physical indicators returned to normal, the position was successfully released on March 16.
Shen Xiaohui, Director of the Department of Hematology, Gansu Provincial Hospital of Traditional Chinese Medicine, introduced that hematopoietic stem cell transplantation is a high-dose chemotherapy or other immunosuppressive pretreatment to remove tumor cells or abnormal clonal cells in the recipient, blocking the pathogenesis, Then transplant autologous or allogeneic hematopoietic stem cells to the recipient, so that the recipient can rebuild normal hematopoiesis and immunity, and achieve a therapeutic effect.
Medical staff taking care of patients
It is reported that the collection of hematopoietic stem cells is generally divided into two types: bone marrow. Stem cell collection and peripheral blood stem cell collection. Bone marrow stem cell collection requires the donor to be anesthetized, and bone marrow fluid is drawn from multiple points in the iliac bone with a bone piercing needle, which is slightly more painful than peripheral blood stem cell collection. Peripheral blood stem cell collection is extracted from venous blood, and stem cells are separated from whole blood using a blood cell separation and collection machine. Under normal conditions, hematopoietic stem cells exist in the bone marrow, and the number of stem cells in the peripheral blood is very small, so it is necessary to inject a mobilizing agent in advance to release the stem cells into the peripheral blood for easy collection.
From the whole process of stem cell mobilization, collection, cryopreservation, and infusion, the patient’s Ms. Yang’s progress was relatively smooth.
Text · Picture: New Gansu · Rush News reporter Ouyang Haijie