[Encyclopedia of Life] How many diseases can the panacea ointment erythromycin cure? What is the difference between erythromycin eye ointment and erythromycin ointment? Here comes the answer

Accidentally burnt?

Rub some erythromycin!

How many bags have you been bitten by mosquitoes?

Rub some erythromycin!

Have pustules and acne?

Rub some erythromycin!

The corners of the mouth are rotten?

Let’s rub some erythromycin…

Speaking of erythromycin ointment, I believe everyone is familiar with it. It can be said that it is a very common type of topical ointment in daily medicine. But there are also many people who have doubts. Do erythromycin ointment and erythromycin eye ointment, which are only different in one word, have the same effect? What’s the difference between the two? Are there any taboos?

1. Source and function

Erythromycin is derived from Streptomyces erythromycin extracted from the culture medium. As a natural macrolide antibiotic with a 14-membered ring, its antibacterial spectrum is similar to that of penicillin. Diphtheria bacillus has a strong inhibitory effect; it also has a certain inhibitory effect on Gram-negative bacteria, such as Neisseria gonorrhoeae, Helicobacter, Bacillus pertussis, Brucella, Haemophilus influenzae and Legionella pneumophila; Spirochetes, chlamydia and rickettsia also have a certain role.

The natural size of the 14-membered ring Overview of cyclic lactone antibiotics

2. Mechanism of action

Red The mechanism of action of mycin is mainly to bind irreversibly to the specific site of the 50S subunit of the bacterial ribosome, inhibit the peptide acyltransferase, and affect the displacement process of the ribosome, thereby preventing the extension of the peptide chain and inhibiting the synthesis of bacterial proteins.

Bacterial protein overview

3.Clinical application

Erythromycin can As an alternative drug for penicillin allergic patients, it is used for upper and lower respiratory tract infections caused by sensitive strains such as hemolytic streptococcus and pneumococcus; scarlet fever and cellulitis caused by sensitive hemolytic streptococcus ; Diphtheria and diphtheria carriers. In addition, it can also be used for Legionnaires’ disease, mycoplasma, chlamydia and other respiratory and urogenital infections.

Erythromycin ointment and erythromycin eye ointment are only one word apart, but there are many differences in the way they are used and their efficacy.

Different indications: Erythromycin ointment is an over-the-counter drug commonly used in dermatology and is suitable for purulent skin diseases such as impetigo, small area burns, ulcer surface infection and acne vulgaris. It is mainly used for different degrees of skin damage and minor infections. In addition, erythromycin ointment is also used to stop nosebleeds, combined with vitamin B2 to treat bacterial angular stomatitis and other treatments.

The main component—the concentration of erythromycin is different: Although the main component of both is erythromycin, the amount of erythromycin contained is different. But it is different. The concentration of erythromycin in erythromycin ointment is 1%, while the concentration of erythromycin eye ointment is 0.5%. If misused, erythromycin eye ointment may not achieve the therapeutic concentration required to fight skin infections.< /span>

< span>Different degrees of sterility: In the production process of these two preparations, the preparation process of erythromycin eye ointment is aseptic operation, while the preparation process of erythromycin ointment does not require sterility.< /span>

< span>Different particle size and irritation: Erythromycin eye ointment is required to be prepared into a very fine powder during the preparation process, and the particles are very small and non-irritating to the eyes.

The requirements for erythromycin ointment on particles are relatively loose. Spreads on the skin without being irritating. Therefore, do not use erythromycin ointment on the eye.

Refer to “Guidelines for the Clinical Application of Antibacterial Drugs” (2015 edition) “Precautions for the use of macrolides, the following points should be paid attention to when using erythromycin eye ointment:

< span>1. Patients who are allergic to erythromycin and other macrolides cannot use.

2.Erythromycin should not be used in combination with terfenadine to avoid causing Cardiac adverse reactions.

3.Patients with hepatic impairment need to reduce the dose appropriately if needed And regular review of liver function.

In addition, < span>Erythromycin is also an antibiotic. When using any antibiotics, the concept of “reasonable use” should always be observed, and a doctor or clinical pharmacist should be consulted before use. In addition, pay attention to the use cycle. Even if the condition improves, you should take the medicine according to the complete prescription, but it cannot be used for a long time.

Overuse and abuse can cause bacteria to become resistant, if bacteria are resistant to all antibiotics All are resistant, and we will enter a post-antibiotic era with no drugs available, where common infections and minor injuries are at risk of death.

If resistance develops

In the event of a serious infection such as mycoplasma pneumonia< /span>

There may be no medicine available

Remind everyone here

It is best not to use drugs with drug resistance for a long time

So as not to bring hidden dangers to your health!