Don’t over-treat cancer! Academician admits: to improve the quality of life of patients, long-term survival

For two consecutive years, after a physical examination, Grandpa Zhang was told that “there is a nodule in the thyroid gland, and further examination is recommended”. But he heard that thyroid nodules are very common, he has no symptoms, he can eat and sleep, so he doesn’t take it seriously.

But after my daughter found out, she was uneasy, so she still took him for a thyroid B-ultrasound. The doctor swept back and forth across Grandpa Zhang’s neck with the probe, and suddenly said, “You don’t feel comfortable with the growth of this nodule. You may need to have a puncture.”

Grandpa Zhang was a little flustered after hearing this, but the final pathological result showed that it was thyroid cancer. However, do not recommend surgery after receiving the report. Grandpa Zhang was in a panic: How can he die if he has cancer in his body?

I. Looking at cancer from a different angle: it is not necessary to kill cancer cells.

When it comes to cancer, many people feel heartbroken and want to kill it.

But academician of Chinese Academy of EngineeringFan Daimingin an interview, he said:To treat cancer, we must start with retreat. Some cancers are cut with a scalpel, killed with chemotherapy drugs, and irradiated with radiation. The patient suffers, but the cancer cells are not completely eliminated in the end. Some patients even died, but the cancer cells in the body were still alive. So, for those cancer cells that cannot be killed completely, can’t be killed, and can’t be killed , must we kill them all, and burn all the jade and stones?

In fact, it is not necessarily, but another way of thinking, find a way to peacefully coexist with cancer cells and achieve long-term survival strong>, maybe you can get good results. Tumor palliative care is to adopt the concept of peaceful coexistence with cancer cells, which not only inhibits cancer cells, but also improves the quality of life and achieves the goal of long-term survival with tumors.

Second, these cancers, drugs may be able to control

clinical On the other hand, after some cancers are diagnosed, there is no need to rush to remove them by surgery, and they may be controlled with drugs.

1. Some thyroid cancers

thyroid cancers are relatively “good” cancers. Some thyroid cancers can be controlled without surgery and by taking medicine for life. If it is a small cancer, it is generally not necessary to perform total thyroid dissection, and postoperative radiotherapy and chemotherapy are not required. The 5-year survival rate is as high as 95%.

2. Chronic myeloid leukemia

There are many types of leukemia, such as acute childhood Lymphocytic leukemia, adult acute promyelocytic leukemia, chronic myeloid leukemia, etc. Leukemia is not a terminal disease. As long as it is detected early and treated in a standardized manner, its cure rate is relatively high among tumors.

Taking chronic myeloid leukemia as an example, targeted drugs with significant curative effect can be used clinically. Lifelong medication is required to control the disease, and some drugs can be reimbursed by medical insurance.

3. Early prostate cancer< /p>

The diagnosis rate of early-stage prostate cancer is relatively high. According to NIH data, more than 11% of men will be diagnosed with prostate cancer in their lifetime, of which 70% are in the early stage. Prostate cancer progresses more slowly, and only about 3% of patients die from it.

Currently, the main methods for the treatment of prostate cancer include surgery, radiotherapy and chemotherapy, observational therapy and so on. However, surgery and chemoradiation can cause side effects and reduce quality of life. In contrast, observational treatment is more advantageous for some early-stage patients.

Washington University School of Medicine tested 731early-stage prostate cancerpatients for up to 20 years A follow-up survey in 2018 found that 61.3% of the patients in the surgical treatment group died, and 66.8% of the patients in the observation treatment group died.

Third, Cancer Treatment Beware of Overtreatment

In cancer treatment, patients are most afraid of overtreatment. Today, whether it is surgery, radiotherapy and chemotherapy or targeted therapy, they are all facing the phenomenon of overtreatment.

  • Surgery

The cleaner the surgery, the better , and even the surrounding normal tissue and possible metastatic sites should be cut off? Blindly expanding the scope of surgery may be counterproductive, not only failing to achieve the purpose of radical cure, but also possibly damaging blood vessels and nerves, causing other complications and increasing the suffering of patients.

Nowadays, there are strict requirements for the surgical resection range of different cancers in medicine. The exact amount of resection needs to be analyzed on a case-by-case basis, but most of them are 3 to 5 cm from the edge of the tumor.

  • Chemotherapy< /li>

For most cancer patients, in order to enhance the curative effect, postoperative radiotherapy and chemotherapy is a common method. However, chemoradiotherapy can have different degrees of side effects, ifBlindly increasingthe frequency and dose of chemoradiotherapy may multiply the toxic and side effects and shorten the survival of patients.

  • targeted therapy

Although targeted therapy Applications are becoming more widespread, but not for all cancer patients. Taking lung cancer as an example, the EGFR mutation rate in Chinese is only 40%, which means that 60% of patients are ineffective against EGFR-TKI drugs, which is why genetic testing should be done before targeted therapy. Blindly listening to the effect of targeted therapy may not achieve the desired effect.

In the field of cancer treatment, the concept of “people-oriented, survival with tumors” is more and more recognized by doctors. .

Fourth, if your loved ones suffer from these cancers, you should be careful

Of course, some cancers with familial hereditary characteristics are worthy of attention and regular inspections , eliminate the risk.

First of all, the better knownBreast cancer. If someone has an immediate family member with breast cancer, her risk of developing breast cancer is 3 times higher than the general population. If two immediate family members have breast cancer, her risk of developing breast cancer is seven times higher than the average person.

It is recommended that such people undergo regular mammography and mammography examinations.

followed by stomach cancer. 5%-10% of gastric cancers are hereditary gastric cancers, especially hereditary diffuse gastric cancer syndrome, which has a higher hereditary probability. If there are at least 2 patients with gastric cancer in first- or second-degree relatives, and at least 1 has diffuse gastric cancer, endoscopy should be performed as soon as possible.

HCC also has obvious familial aggregation and genetic susceptibility, and the heritability of liver cancer in first-degree relatives is ( 58.74 ±5.43) % . For people with a family history of liver cancer, a full liver function test, B-ultrasound and other tests should be carried out.

Finally, lung cancer, with familial aggregation phenomenon, close relatives are at high risk of cancer 2 times. The study also found that women with a family history of lung cancer had a higher risk of developing lung cancer than men. Annual lung cancer screening is recommended for this population.

In the face of cancer, patients do not need to panic, they should calm down first, believe in science, not Blind treatment, overtreatment. Cancer does not necessarily need to be eradicated, and the treatment plan can be customized according to one’s own situation to improve the quality of life, or to achieve tumor-bearing survival.

# Yaozero Zero Plan# #Health2022#

References:

[1] Academician Fan Daiming: use The philosophy of twisting Yangko in the treatment of tumors. Physician Report. 2016-07-02

[2]NEJM: 20-year follow-up found that compared with observational treatment, prostatectomy has no obvious benefit for early-stage patients | Clinical Great Discovery. Singularity Network. 2017-07-26

[3]Be careful! If a family member is suffering from these cancers, you have to be careful! .Health Times.2019-02-11

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