On April 21, local time, the latest notification from the British health department stated that, 34 new cases of unexplained hepatitis in young children have been identified in the UK, bringing the total to 108, the investigation revealed. Of the confirmed cases, 79 are in England, 14 are in Scotland and the rest are in Wales and Northern Ireland. Of these cases, eight children received liver transplants because of their severe condition. On 5 April, UK health authorities notified WHO of 10 cases of Cases of severe acute hepatitis in infants and young children of unknown etiology. The patients were between 11 months and 5 years of age and had no prior medical history. The earliest 1 case developed symptoms in January 2022, the remaining 9 cases were detected in March, and all 10 cases were detected during hospitalization. By April 8, further investigations across the UK had found a total of 74 similar cases. The British side stated that unexplained hepatitis mainly occurs in children under the age of 10. The clinical syndrome of confirmed cases is acute hepatitis, significantly elevated liver enzymes, usually accompanied by jaundice, and sometimes gastrointestinal symptoms. “We are rapidly investigating possible factors that may lead to hospital admissions for children with hepatitis. Dr Meera Chand, Director of Clinical and Emerging Infections at Public Health Safety England, said, “Increasingly, the information gathered through our investigations suggests that these cases are associated with adenovirus infection. However, we are Thoroughly investigate other potential causes.”The investigation also showed that information from patient samples and monitoring systems An unexplained hepatitis etiology pointed to a link to adenovirus infection, and 77% of tested cases were positive for adenovirus. Adenoviruses are a common group of viruses that usually cause a range of mild illnesses, including colds, vomiting, and Diarrhea, usually not caused by hepatitis. Adenoviruses are an important cause of febrile illness in young children, most commonly causing upper respiratory syndrome, but also pneumonia. Rarely, it can cause diseases of the digestive system, eyes, genitourinary system and nervous system. Adenoviruses are usually spread from person to person and through contact with contaminated surfaces and through the respiratory tract spread. The most effective way to reduce the spread of adenovirus is to maintain good hand and respiratory hygiene and supervise young children to wash their hands thoroughly. While mild hepatitis is common in children, this time is markedly different, experts say Some patients in the UK are in serious condition, and some even require liver transplants. Experts say adenoviruses rarely cause severe hepatitis in healthy people. It is very rare for this to occur in children without serious underlying health problems. UK Health is actively investigating other possible contributing factors, such as another infection, including ) or environmental reasons. Health officials have ruled out any link to the Covid-19 vaccine because no patients have been vaccinated against Covid-19. UK Health also said it was working with scientists and clinicians across the country to study the genome of the adenovirus Has anything changed to answer the above question as soon as possible. Statistically, Up to now, at least 8 European and American countries have reported more than 100 cases of suspected unexplained hepatitis in young children.
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