Recently, an article “14 rectal cancer patients recovered after testing new drugs, one dose of 73,000 yuan” attracted everyone’s attention.
According to foreign media reports, a new study published in the “New England Journal of Medicine” shows that:
From the Memorial Sloan-Kettering Cancer Research in the United States In a small clinical trial, pharmaceutical company GlaxoSmithKline’s immunotherapy drug called dotalizumab was found to be effective in curing rectal cancer.
The researchers conducted the experiment with 14 patients with locally advanced rectal cancer, after 6 months Following the test investigation, combined with physical examination, endoscopy and other examinations, the existence of rectal cancer cells was not detected.
However, this drug is not cheap. The cost of each dose of dotalizumab is about 11,000 US dollars, which is equivalent to about 73,000 yuan. Considering that if it is launched in the future, the price of this drug will be will be higher.
Of course, this clinical study still has certain limitations, and the scope of its research needs to be further expanded in the future.
Intestinal cancer is not to be ignored
Both foreign and domestic studies have shown that: As the age continues to increase, the incidence of colorectal cancer is gradually increasing, especially in the 40-50 years old.
The occurrence of colorectal cancer is often caused by age, genetic factors, and dietary habits. The good time has also been missed.
Always diarrhea, is it a precursor to bowel cancer?
Actually, diarrhea is not the only or representative precursor of bowel cancer. The early symptoms of bowel cancer are not obvious and are often easily overlooked.
And usually diarrhea is mainly caused by these 3 factors:
First, unsanitary diet
We often eat roadside stalls and takeaways. The quality of these products is difficult to guarantee, and raw materials deteriorate and processing pollution is common.
Eating these foods often can easily lead to diarrhea, and may even induce severe food poisoning, threatening the life safety of patients.
Second, unhealthy diet
In recent years In recent years, more and more people have frequent diarrhea. The occurrence of this situation is closely related to changes in dietary environment and dietary conditions.
Abstaining from eating vegetables for a long time will not only increase excessive calorie intake, resulting in a large amount of fat accumulation, but also easily lead to indigestion, bloating, diarrhea > and so on.
Third, gastrointestinal diseases
Diarrhea is a very common symptom that may be caused by a variety of digestive diseases, such as enteritis, dysentery, intestinal dysfunction, abdominal cold, food poisoning, etc.
Therefore, it cannot be said that frequent diarrhea is necessarily colon cancer.
If the patient simply shows symptoms of diarrhea, the possibility of bowel cancer is relatively low. Diarrhea caused by colon cancer will show certain specific symptoms, and it will also be combined with other digestive system symptoms and systemic symptoms.
If there is a significant increase in the stimulation of diarrhea, which can reach several or even more than ten times a day, and even obvious blood in the stool will appear, it is recommended that the patient must pay attention to it and conduct relevant examinations in time.
What are the inspection methods for this disease?
1. Digital rectal examination
Digital rectal examination, the doctor will put the index finger into the patient’s anus to check whether there is any lump in the patient’s rectum Appear. This kind of inspection can detect 60% to 70% of rectal cancer, and is a relatively simple, economical and effective inspection method.
2. Endoscopy
The scope of endoscopy is different from the location, so it can be divided into anoscopy, colonoscopy, and sigmoidoscopy. This inspection canObtaining case diagnosis through biopsy is an important basis for formulating subsequent treatment plans.
3. Laboratory inspection
Experiment Laboratory examinations include a number of tests, such as fecal occult blood test, tumor markers, immunohistochemistry and genetic testing.
The fecal occult blood test is the main method for screening the disease. Tumor markers can evaluate the disease and detect recurrence. Generally, the markers to be tested for the disease are CEA and CEA strong>CA19-9.
Immunohistochemistry and gene monitoring can recommend detection of mismatch repair protein expression and guide patients’ medication.
4. Barium meal X-ray
Barium meal X-ray is currently the most commonly used and most economical examination method for the diagnosis of the disease, which can detect superficial mucosal lesions in early stage patients as well as lesions in middle and advanced stages.
5. CT
CT is an important method to determine the stage of the disease before surgery, which can clearly show the degree of colorectal cancer’s external invasion and lymph node metastasis. situation, and at the same time determine the possibility of tumor resectability.
In addition, MRI can also show the invasion of the lesions and surrounding tissues, and can be combined with CT, which is especially suitable for preoperative diagnosis and surgical evaluation of the disease, but the cost is relatively high.