Insulin resistance, hyperinsulinemia and progression to diabetes all increase cancer risk, a 30-year follow-up published in the British Journal of Cancer (BJC) in March 2022 found.
The study found that the incidence of cancer in patients with normal glucose tolerance, impaired glucose tolerance and diabetes was 6.06, 6.77 and 7.18 per thousand people per year, respectively. The researchers point out that the study confirms that diabetes, hyperglycemia and hyperinsulinemia are clearly associated with cancer.
The analysis found that compared with normal people, the cancer risk of patients with impaired glucose tolerance and diabetes increased by 77% and 2.34 times, respectively. Once impaired glucose tolerance progresses to diabetes, the risk of cancer doubles.
The study also showed that increased blood sugar levels were significantly associated with cancer in people with large blood sugar fluctuations, but no such association was found in people with small blood sugar fluctuations. ①②This also suggests that people with diabetes should pay more attention to controlling their blood sugar.
About half of adults with abnormal blood sugar
A “National Epidemiological Survey on the Prevalence of Diabetes in Chinese Population” published in April 2020, sampled and analyzed Chinese Diabetes prevalence data of a total of 75,880 residents in 31 provincial-level administrative regions in mainland China, the results found:
1. Nearly half of adults have abnormal blood sugar
The total standardized prevalence of diabetes among adult residents in my country was 12.8%, and the standardized prevalence of prediabetes was 35.2%.
2. The prevalence of diabetes increases with age
The prevalence of both men and women increases with age: prevalence of diabetes after age 40 The prevalence of pre-diabetes has reached 20.2% among people aged 18-29, and more than 40% of people after the age of 40 are in pre-diabetes.
3. The North has the highest overall prevalence
Including diagnosis and prediabetes, the overall prevalence is the highest in the North, followed by the Southwest, Northeast, South, Central, East and Northwest area. ③
Have a good blood sugar, you need to know these 4 points
1. It is very important to eat the first bite
Big fish and big meat, high protein, high Sugar, heavy oil and salt are not good for blood sugar health. In addition, the order of meals can also affect blood sugar fluctuations.
Some studies have pointed out that the eating order of “vegetables-protein meat-staple food” has the best effect of controlling postprandial blood sugar. In short, the staple food should be eaten last; if it is unacceptable, then eat vegetables first , and then eating one bite of meat and one bite of rice is good enough. ④
It is recommended to try the “Jiangnan Diet” more often:
1) Increase coarse grains and reduce polished rice and noodles;
2) Recommended vegetable oil, low temperature cooking;
3) Increase white meat and reduce red meat, soy products are recommended;
4) The more vegetables, the better the amount of fruits;
5) The recommended amount of nuts, milk
6) The cooking methods of steaming, boiling and rinsing are strongly recommended. ⑤
2. Lack of sleep can also affect blood sugar
Gao Shan, chief physician of the Endocrinology Department of the Western Hospital of Beijing Chaoyang Hospital, pointed out in an interview with a Health Times reporter in 2017 that long-term lack of sleep can lead to a A series of negative physiological changes, such as sympathetic excitation, activation of the stress system, increased secretion of “glucose hormones” such as cortisol and epinephrine in the body, can also cause insulin resistance.
Insulin resistance reduces the efficiency of insulin to promote glucose uptake and utilization in the human body, and the body compensatively secretes excessive insulin to produce hyperinsulinemia to maintain blood sugar stability. If this condition is not improved for a long time, it may lead to diabetes. ⑥
3. Exercise can really improve blood sugar
Many endocrinologists have mentioned that “muscle is a good hypoglycemic agent”. In an interview with Health Times in 2015, Sun Zilin, chief physician of the Endocrinology Department of Zhongda Hospital Affiliated to Southeast University, also said that in some cases, the effect of some hypoglycemic drugs is less than 1. Sugar effect can reach 1.8. This means that effective exercise may even be more effective in anti-glycemic than some drug treatments. ⑦
He said that moderate-intensity aerobic exercise combined with low-intensity resistance exercise can better achieve hypoglycemic effect. Aerobic exercise can burn energy, such as tai chi, jogging, square dancing, brisk walking, etc. Practicing dumbbells, strength training belts and other resistance exercises can reduce fat, promote muscle growth, improve skeletal muscle antioxidant capacity, improve insulin resistance, and make hypoglycemic drugs more effective.
4. Fat in the stomach is the most dangerous.
Generally, people with thick waists and large stomachs have a higher risk of diabetes. A Health Times reporter once interviewed an endocrinologist. When it comes to diabetes, the first thing he emphasizes is abdominal obesity!
A study “Relationship between Central Obesity, Impaired Glucose Regulation, and Type 2 Diabetes” published by Qingdao CDC in 2014 pointed out that abnormal waist-to-hip ratio caused by central obesity is closely related to blood sugar regulation. Abnormalities are associated with the onset of type 2 diabetes. ⑧
The “Guidelines for the Prevention and Control of Overweight and Obesity in Chinese Adults” compiled by the former Department of Disease Control of the Ministry of Health clearly stipulates that the waist circumference of men is ≥85 cm, and the waist circumference of women is ≥80 cm.
This article is synthesized from:
① Cancer and its predictors in Chinese adults with newly diagnosed diabetes and impaired glucose tolerance (IGT): a 30-year follow-up of the Da Qing IGT and Diabetes Study. Br J Cancer. 2022 Mar 7.
② 2022-03-12 China Circulation Journal “High blood sugar increases cancer risk! 30-year follow-up survey of the Daqing study”
③ Li Yongze, et al. BMJ, DOI: 10.1136/bmj.m997
④ Sun, L., Goh, HJ, Govindharajulu, P ., Leow, MKS, Henry, CJ (2020). Postprandial glucose, insulin and incretin responses differ by test meal macronutrient ingestion sequence(PATTERN study). Clinical Nutrition, 39(3), 950-957.
⑤ 2020-06-02 Health Times “What’s so good about the “Jiangnan Diet” praised by academicians? 》
⑥ 2017-09-05 Health Times “Children are prone to diabetes”
⑦ 2015-01-05 Health Times “Smart exercise beats hypoglycemic drugs”
⑥ 2017-09-05 p>
⑧ 2014 Qingdao Center for Disease Control and Prevention, “The relationship between central obesity and impaired glucose regulation and type 2 diabetes mellitus.Department”, Liu Li, Shao Yuhan