Rational Drug Use|Talking about Medicine in Three Minutes–The Hormone Family: The Little Secret of Topical Hormone Ointment

Video duration 3 minutes46seconds

If someone asks, who is the “big brother” in dermatology? The answer must be “Topical steroid cream!!!as a solution to the skin The question of “Elixir“, topical hormone ointment is very popular among mothers. But in addition to use, it will also cause many concerns.

Today, Zhang Xiaoyue, a pharmacist from Henan Provincial Children’s Hospital, will reveal the little secret of topical hormone ointment and talk about how to choose glucocorticoid ointment correctly .

Classification of hormone ointments

What we usually call hormone ointments refers to topical glucocorticoids. According to the strength of the effect, topical glucocorticoids are usually divided into four categories in clinical practice, namely, super strong, strong, moderate and weak. .

Approved“Expert Consensus on Standardizing Topical Glucocorticoids” The following table is summarized, you can pick up the ointment at home and compare it~

sort

name< /span>

Scope< /span>

Super strong Effective

0.05%Clobetasol propionategels, ointments, creams and foams;0.05%difluocinolone acetate ointment;0.1%fluocinolone ointment wait

For severe, hypertrophic skin lesions (psoriasis, lichen planus, hypertrophic eczema, neurodermatitis, etc.)

generally everyWeekly medication should not exceed 50 g;

Continuous medication should not exceed 2 – 3weeks;

< span>Try not to use< 12year-old children;

< span>Should not be used for a long time in a large area;

unless special needs,< span>Generally, it should not be used on the face, breasts, pubic area and folds.

Powerful

0.05% Halometasone cream, 0.1% mometasone furoate ointment, 0.005%Fluticasone Propionate Ointment,0.1%Triamcinolone Acetonide Ointment,0.5%Triamcinolone acetonide cream, etc.

Medium

0.1%mometasone furoate cream and lotion,0.1%< strong>Hydrocortisone butyrate ointment, creams and lotions, 0.05 %fluticasone propionate cream,0.1%triamcinolone acetonide milk Ointmentsand ointments, lotions, etc.

Suitable for mild to moderate skin lesions (initial treatment of atopic dermatitis, seborrheic dermatitis and other eczema dermatitis) span>

can be applied continuously4 ~ 6weeks; span>

< 12-year-old children should try not to use more than 2weeks;

should not be used in large areas for a long time.

weak

0.05% Desonide ointment, 0.1% Betamethasone Valerate Lotion, 0.01%Fluocinonide Cream, 0.025%< /span>Triamcinolone acetonide cream and various topical formulations of hydrocortisone, prednisone and dexamethasone, such as, 0.5% span>Prednisone Acetate Ointment,0.05%Dexamethasone Acetate Ointment< /strong>, 0.025%hydrofluoroacetate Loose ointment, etc.

for light Severe and moderate lesions (including childhood dermatology, face and tender skin) p>

can be used in a large area for a short time, and can be used for a long time if necessary.

strong Comparison of absorption of hormone ointments

When choosing topical glucocorticoid ointment, it is not the stronger the better! The absorption rate of each part of the body from high to low is: mucous membrane > scrotum > eyelid > face > chest and back > upper arm and thigh > forearm and calf > dorsum of hands and feet > palms and soles > nails.

In conclusion: high absorption rate Generally, weaker hormones are selected for the parts, and vice versa; weaker hormones are selected for the head, face and perineum, the four limbs are selected for the trunk, and the stronger ones are selected for the hands, feet, and back.

Special populations and areas< /strong>

strongA weaker or softer hormone is generally chosen.

②Pregnant or lactating women: Use with caution during pregnancy, if necessary If so, choose moderately weak hormones. Fluorinated hormones are contraindicated in early pregnancy and should not be applied to the breast during breastfeeding.

③ For the thick hair area, you can choose hormones of appropriate strength according to the skin lesions.

Dosage Tips

“a small amount, thinly”how to judge a layer?

We usually use “Fingertip Units (FTU)” to estimate topical dosage The dosage of one fingertip is about 0.5g, which can be applied to an area the size of two palms of an adult, and topical hormone ointment is usually 1-2 times a day.”

content_title” responsive” sizes=”(min-width: 320px) 320px, 100vw” src=”https://mmbiz.qpic.cn/mmbiz_png/dYQOq0yvTtDc2fDK3MBg8MoicWCXDiccZbKjKzpoETIl0DiaibFpYgFbnicMHSpoCLSPlcP5165CAo2Vtldiciapia975Q/640″ width=”600″>Author: Xiaoyue Zhang p>

Review: Zhang Shengnan

< span>Zhang Xiaoyue     < /strong>

Henan Children’s Hospital

Pharmacist,Master student

Use what I have learned and do my best to help everyone in need

Rational drug use in China”

“Rational Drug Use in China” will launch a series of original short videos on “Rational Drug Use Science” in 2022, opened the “Three Minute Drug Talk” video column, Focus on clinical rational drug use, drug science popularization, new drug review, and smart pharmacy. Long-term collection of short videos, invite people with lofty ideals!

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Tel: 010-83025717 span>

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China Rational Drug Use Exploration Journal

Previous name: strong>“Chinese Licensed Pharmacists”

Publishing Period:Monthly

ISSN:2096-3327

CN:

strong>10-1462/R (formerly CN: 11-5132/R)

Place of publication:Beijing

Published:2003

《 China Rational Drug Use Exploration (formerly “China Licensed Pharmacist”) was founded in 2003. It is a professional academic journal of medicine sponsored by the State Drug Administration, China Health Media Group and China Pharmacists Association. This journal is RCCSE China’s core academic journals, included in China’s core journals (selection) database, CNKI China Journals Full-text Database, American “Chemical Abstracts” CA (2014), Chinese Science and Technology Periodicals Database (VIP), JST Japan Science and Technology Agency Database (Japan), U.S. “Ulrich Journal Guide” (UPD).