內容目錄
1. What should I do if the antitumor drug is missed?
In the vast majority of cases, if you miss a dose once and the interval is not long, you should make up for it.
If the time until your next dose is very short, the missed dose should not be taken. Because the drug has been used for a long time, the blood concentration has been stabilized. Taking one less dose may not have much effect on the efficacy, but if you eat twice the next meal, especially antitumor drugs, serious adverse reactions may occur. For details, please refer to the instructions, or consult your doctor or pharmacist.
2. Can I break it apart or crush it to eat if I have difficulty swallowing?
All sustained-release tablets and enteric-coated tablets cannot be crushed or chewed. Forcibly breaking it apart will destroy the structure of the tablet, so that the tablet core containing the drug will be directly exposed, and the drug will be released suddenly. But there are a few parts that can be taken apart:
(1) Read the instructions: the instructions list the usage of “half tablet”, you can break it up and eat; if the instructions say “swallow whole” Do not break or crush”, you can only take the whole tablet.
(2) Look at the nicks: ordinary compressed tablets are not coated, as long as there are nicks on them, they can be taken apart.
3. Will taking other medicines at the same time have any effect?
Be aware of food-drug interactions, such as grapefruit juice, antacids, antibacterials, and antiepileptics, which may affect drug absorption and metabolism when taken together.
4. Can I reduce the dose or stop eating if I have adverse reactions or can not tolerate it?
In the process of using anti-tumor drugs, do not arbitrarily reduce the dose or stop eating and drinking, which will affect the efficacy of the drugs and even cause drug resistance. At the current medical level, common adverse drug reactions can be treated. After doctors deal with adverse drug reactions in a timely manner, in some cases, medication can be continued.
5. How should anti-tumor drugs be stored and used at home?
For medicines without special temperature indication, they can generally be stored at room temperature. The recommended temperature is 10~30°C. Specifically, store them according to the “storage” requirements under the instructions. For some oral medicines that need to be stored in a cold place, when taking them home from the hospital, it is recommended to bring a portable refrigerator to ensure the quality of the medicines on the road. When administering, gloves should be worn to avoid direct contact with the drug.
6. Is it better to take it on an empty stomach or after meals?
Some oral antitumor drugs are recommended to be taken on an empty stomach, because taking them with food or a high-fat diet will affect drug metabolism and thus affect the efficacy or adverse reactions. The specific method of taking is subject to the instructions.
7. What are the precautions for taking antitumor drugs at home?
Take the medicine on time and in the correct amount, and be sure to follow the doctor’s advice. The daily medication situation and adverse reactions during the medication process can be recorded, so that the doctor or pharmacist can be informed in time for follow-up visits. Regularly review the blood routine and liver and kidney function. If you have chest tightness, palpitations, fatigue, fever, severe diarrhea and rash, you must seek medical treatment in time.
Expert introduction: Gu Haijuan, Deputy Director of the Pharmacy Department and Deputy Chief Pharmacist of Nantong Cancer Hospital, is good at individualized medication of anti-tumor drugs guided by pharmacogenomics and therapeutic drug monitoring.
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