Source: Science China (ID: Science_China)
Expert of this article: Pan Kunming, Master of Pharmacy, Peking University, Chief Pharmacist of Zhongshan Hospital Affiliated to Fudan University
Recently, a news #Woman was almost paralyzed by nitrous oxide for 3 months#Aroused attention, which sounded the alarm for us.
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According to reports, Ms. Wang tried to inhale nitrous oxide six months ago. As a direct consequence, she was unable to walk upright.
The police remind: “laughing gas” is hallucinogenic and addictive, and long-term inhalation can cause organ dysfunction. Do not smoke!
דlaughing gas”, what is it?
“Laughing gas”, the chemical name is nitrous oxide, is a colorless, non-flammable, slightly sweet gas.
“Naughting gas” is used as anesthetic or analgesic due to its pharmacological effects such as anesthesia and analgesia It has a history of more than two hundred years. Clinically, it can also be used for pain relief in gynecological labor, anti-anxiety in dental care, improvement of withdrawal symptoms, refractory depression, etc.
In addition, because of its antibacterial, non-flammable and odorless properties, “laughing gas” is often used as a food additive. In the “National Food Safety Standard for Use of Food Additives” (GB2760-2014) issued by the National Health and Family Planning Commission,nitrous oxide is listed in the “list of processing aids that require specified functions and scope of use” “, is approved as a propellant, foaming agent.
(Picture: From “National Food Safety Standard for Use of Food Additives” (GB2760-2014))
< p>“Laughing gas” is safe to use under specified circumstances, but a very small number of people buy and sell it illegally. This is the main source of the current misuse of “laughing gas”. Addicts inflate gas from a micro-compression device of nitrous oxide gas into a balloon and inhale in pursuit of physical euphoria and psychedelic effects.
דlaughing gas”, does it really make people laugh?
“< /span>laughing gas”, first time in the late 18th century It was found that a British scientist, Humphrey Davy, later discovered that inhaling “laughing gas” can produce a highly pleasant state of excitement, causing People dance and laugh, so it is named “laughing gas”, its mechanism of action It is mainly related to the release of dopamine and other excitatory neurotransmitters in the body.
“Laughing gas” is a hazardous chemical.
In February 2015, the State Administration of Work Safety and ten departments jointly issued the “Catalogue of Hazardous Chemicals” (2015 Edition). “Laughing gas” is a dangerous product in the catalog, serial number 2561, product name: nitrous oxide (compressed or liquefied); alias (nitrous oxide; laughing gas).
The production, storage, use, operation and transportation of “laughing gas” without corresponding licenses are all illegal. If the market order is disturbed, the circumstances are serious and can be sentenced to prison.
×What harm does the abuse of “laughing gas” have?
The main harm of “laughing gas” abuse is the nervous system, < span>Blood system and cardiovascular and cerebrovascular damage, etc.
“laughing gas” is addictive. Compared with physical addiction, mental addiction is stronger, so it is easy to abuse, Long-term toxicity requires more vigilance!
Nervous System Harm:Inhalation of “laughing gas” may cause a series of damage to the brain and nervous system. Including: myelopathy, peripheral neuropathy, polyneuropathy, neuropsychiatric diseases, cerebral cortical lesions and focal necrosis of brain parenchyma.
Among them, peripheral neuropathy is characterized by numbness and weakness of the limbs, unsteady walking, paresthesia of the toes, numbness and acupuncture Severe symptoms include falls and inability to walk, loss of coordination and even paralysis.
In addition, neuropsychiatric manifestations include memory loss, difficulty concentrating, learning disabilities, depression, anxiety, Hallucinations, irritability, abnormal muscle tone, athetosis, etc.
Blood damage:< /strong>Anemia is relatively common, and severe megaloblastic anemia and pancytopenia may occur.
Cardiovascular and cerebrovascular hazards:can speed up arteries Atherosclerosis, leading to myocardial infarction and stroke; increased risk of deep vein thrombosis and pulmonary embolism.
Other hazards: may also cause Pigmentation; pneumothorax and submediastinal emphysema, intestinal swelling, ruptured tympanic membrane; dysuria, etc.
Anyway
Dangerous Goods “laughs”
addiction and abuse are highly toxic,
There is a lot of damage to the nervous system,
Early diagnosis and early treatment are the most critical!
Source: Science China (ID: Science_China)
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