Click the blue text above to follow Alzheimer’s disease for free now
showed that simple dietary interventions could save billions of dollars in healthcare costs.
< /p>Neuroscience News, June 9th
The Fatty Acid Research Institute (FARI) recently New research[1] published in the journal Nutrients shows that people with higher blood levels of DHA are more likely to develop Alzheimer’s disease than those with lower levels Sex was 49% lower. The study, led by Dr. Aleix Sala-Vila, showed that supplementing a diet with additional omega-3 DHA, especially in those with the ApoE4 gene (the gene that makes people with AD about 50% more susceptible) doubling) may slow disease progression. Such a low-cost, low-risk dietary intervention could potentially save billions of dollars in healthcare costs.
Research published in Nutrients on June 9, 2022 (latest impact factor: 4.546)
This prospective observational study was conducted in the Framingham Offspring Cohort, including 1,490 individuals aged ≥65 years of participants without dementia, the researchers examined the red blood cell (RBC) docosahexaenoic acid (DHA) association with the onset of Alzheimer’s disease (AD), and also tested Interaction with APOE-ε4 vector.
Dr Aleix Sala-Vila, who led the study
<> The highest RBC DHA quintile (Q5, >6.1%) had a 49% lower risk of developing AD compared to the lowest quintile (Q1, <3.8%). From Q1 to Q5, increases in RBC DHA are expected to increase AD-free lifespan by 4.7 years.
Furthermore, the researchers pointed out that increased DHA intake may reduce the risk of AD, especially for those individuals at high risk, such as those with APOE -ε4 allele, suggesting that they may benefit more from higher DHA levels than non-carriers.
Preventing AD’s impact on public health through simple dietary interventions like DHA Also significant. The researchers noted, “Considering the estimated 2021 healthcare costs for all people with Alzheimer’s disease or other dementias in the U.S. of $355 billion (excluding care from family members and other unpaid caregivers) cost), any cost-effective strategy to delay the onset of Alzheimer’s disease is the greatest public health benefit.For a person with AD, delaying AD for 5 years can 2.7 years to live, 4.8 more years to live AD-free, worth over $500,000.”
So how does this report perform in this area? “Our study is consistent with Tan et al. [2], who reported a cross-sectional relationship with RBC DHA on cognitive performance and measures of brain volume (higher DHA) associated with beneficial outcomes),” FARI Chair William S.Dr Harris said.
Tan et al. published in Neurology in 2012 (latest impact factor: 9.91)
Dr. William S. Harris
“The most interesting thing is that 15 years ago, Schaefer et al reported similar findings in the parents of the focus individuals in this survey, the original Framingham Heart Study cohort. Schaefer et al reported that plasma phosphatidylcholorrhea Participants with the highest levels of alkaline DHA had a significantly lower risk of developing all-cause dementia by 47% compared to those with low levels . Similar findings within a similar gene pool, a generation apart, were considerably< strong>Relationship between DHA and dementia is confirmed.”
15-year-old study published in Archives of Neurology
About the Fatty Acids Research Institute (FARI)
The Fatty Acids Research Institute (FARI) is a non-profit research and educational foundation. FARI was established to accelerate the discovery of the health effects of fatty acids, especially the long-chain omega-3 fatty acids EPA and DHA. FARI researchers and scientists will focus on publishing high-quality studies on the multiple associations between fatty acid levels and human (and animal) health outcomes. These studies will improve the ability to predict disease risk and, more importantly, suggest ways to reduce risk by modifying our diets and/or supplementation regimens. www.faresinst.org
Disclaimer
The medical information on this official account is only Provided and shared as an information resource, not for use or reliance on any diagnostic or therapeutic purpose. This information should not be used as a substitute for professional diagnosis or treatment. Please consult your doctor before making any medical decision or guidance regarding a specific medical condition.
Caring for parents and paying attention to “Alzheimer’s disease”