The new crown epidemic has been 3 years old. As an infectious virus with no specific medicine, the most effective way to control it should be a vaccine. To this end, the government has been vigorously promoting the vaccination of the new crown. Compared with some developed countries and regions, my country’s vaccination rate is not the highest. Especially in the outbreak of the new crown epidemic in Shanghai, most of the critically ill and dead infected people have not been vaccinated against the new crown.
Regarding the safety of vaccines, the inactivated vaccines used in my country have been considered very safe in the past, and the probability of serious adverse reactions is extremely low. However, there have been some different voices on the Internet recently. In Baidu Tieba and Xiaohongshu, you can find some messages saying that family members were diagnosed with leukemia within a few months after being injected with the new crown vaccine. I deliberately searched Baidu Post Bar, and most of the leukemia types left by netizens were acute myeloid leukemia, including M2, M3, M4, M5, and some acute lymphoblastic leukemias. Whether the descriptions in these posts are 100% true, we have no way to verify, is there any connection between the vaccination of the new crown and the occurrence of leukemia in these people?
On May 27, the Joint Prevention and Control Mechanism of the State Council held a press conference. At the meeting, Wang Huaqing, chief expert of the immunization program of the Chinese Center for Disease Control and Prevention, introduced that if some symptoms and diseases appear after vaccination, whether they are related to vaccination or not, relevant judgments need to follow standardized procedures and have a basis.
Expert Wang Huaqing pointed out that abnormal reactions to vaccines should be analyzed and judged by an expert group composed of multidisciplinary experts according to the contents of the investigation. Six aspects should be considered in judging adverse reactions. The first is the temporal association; the second is to have biological rationality, for example, live attenuated vaccines are generally not vaccinated for people with immunodeficiency; the third is the strength of the association, which must have significant differences through statistical analysis; Fourth, the occurrence of abnormal reactions is also regular. For example, a larger dose of the vaccine is more likely to cause fever; the fifth is the consistency of the association, that is, whether these people who have been vaccinated have similar symptoms and symptoms. Disease, whether symptoms were higher than baseline; sixth was the specificity of the association, ie whether the vaccine was the only factor.
The pathogenesis of leukemia is quite complex and is the result of the interaction of internal and external factors. From the internal point of view, the patient itself has some kind of congenital susceptibility quality or chromosomal aberration itself. In terms of external factors, there are various pathogenic factors in the environment we live in, such as viral infection, ionizing radiation, many organic chemicals, and various bad habits (smoking, alcoholism, staying up late, etc.). The combined effect of these factors, accumulated over time, causes some gene mutations in hematopoietic cells, activates a certain signaling pathway, and leads to the generation of clonal abnormal hematopoietic cells.
It can be seen that there must be chronic and long-term incentives for the final occurrence of leukemia, and these people who develop leukemia after being vaccinated may be more likely to be just a coincidence in time. After all, leukemia is just like other cancers, and the number of new patients every year is quite high. At present, a total of 3.37 billion doses of the new crown vaccine have been reported nationwide, and the total number of vaccinations has reached 1.289 billion. The number of people covered and the number of people vaccinated in the whole process account for 91.47% and 89.07% of the country’s total population, respectively. In such a huge amount of data, there are very few serious adverse reactions officially reported, which shows that the safety of domestically produced inactivated new crown vaccines is very high. As for the doubts of some netizens, a multidisciplinary expert group is still required to investigate and make scientific judgments before convincing results can be drawn.