Source: People’s Daily Online
May 10 is “World Lupus Day”. The National Clinical Research Center for Skin and Immune Diseases recently released the Education Manual for Patients with Systemic Lupus Erythematosus. People’s Health Online invited experts from rheumatology and immunology to discuss and exchange topics such as the “Education Manual for Patients with Systemic Lupus Erythematosus” and the scientific medication and standardized treatment of patients with lupus erythematosus.
Experts believe that early diagnosis, early treatment, and early control are particularly important for improving prognosis. It is necessary to further popularize lupus erythematosus-related knowledge, standardize lupus erythematosus treatment, and improve patients’ quality of life.
Strengthen disease management by popularizing disease knowledge
Zeng Xiaofeng, director of the Department of Rheumatology and Immunology of Peking Union Medical College Hospital and director of the National Clinical Research Center for Skin and Immune Diseases, said that this release of “Systemic Lupus Erythematosus” Patient Education Manual”, hoping to provide patients with more relatively scientific and complete information, including clinical treatment of lupus erythematosus, medication management and other aspects. In the context of the normalization of epidemic prevention and control, more patients can find professional doctors nearby and cooperate with doctors to manage their own diseases.
“The Educational Manual for Patients with Systemic Lupus Erythematosus provides an important reference for patients’ daily disease management.” Deputy Director of the National Clinical Research Center for Skin and Immune Diseases and Chairman of the Rheumatology Branch of the Chinese Medical Association , Zhao Yan, vice president of the Rheumatology and Immunology Branch of the Chinese Medical Doctor Association, said that early detection, early diagnosis and early treatment mentioned in the manual are the principles of systemic lupus erythematosus treatment. Antinuclear antibody screening is an important basis for the diagnosis of lupus erythematosus. If positive, go to a specialist hospital for further diagnosis and standardized treatment as soon as possible.
Zhao Yan believes that the manual provides patients with relevant knowledge about the treatment of lupus erythematosus, and hopes that patients can take the initiative to grasp the popular science information of the disease, communicate with doctors in a timely manner, and complete the treatment plan together. Zhao Yan explained that as a chronic disease, lupus erythematosus requires long-term regular treatment, regular follow-up, and consistent medication with doctors in order to maintain a relatively healthy state.
As soon as possible standardized treatment improves patient prognosis
Zeng Xiaofeng introduced that in recent years, with the development of science and technology and the emergence of new drugs and new treatment methods, the level of diagnosis and treatment of lupus erythematosus in my country has been improved. However, the long-term survival rate of patients still faces severe challenges. Lupus erythematosus is a chronic disease, and standardized treatment is particularly important. It is necessary to further increase the attention to lupus erythematosus, so that more patients can correctly understand the knowledge of lupus erythematosus diagnosis and treatment, and standardize treatment as soon as possible to avoid the aggravation of the disease.
Tian Xinping, deputy director of the Office of the National Clinical Research Center for Skin and Immune Diseases, member of the Standing Committee and Director General of the Chinese Medical Doctor Association, said that during the treatment of lupus erythematosus, stratified treatment should be carried out according to the patient’s condition. Due to the different clinical manifestations of different patients, professional doctors are required to conduct an overall assessment of the condition, and then standardized treatment can achieve better clinical results. In addition, standardized treatment can also effectively avoid the occurrence of complications, better avoid the side effects caused by drugs, and adjust the medication in time through regular return visits.
Zeng Xiaofeng said that systemic lupus erythematosus can cause autoimmune damage to multiple organs, including immune complex damage and cellular immune damage. Taking the kidney as an example, if it is not treated and controlled in time, it may lead to lupus nephritis, and even lead to renal failure and uremia. It is necessary to control organ damage as soon as possible to avoid irreversible lesions. Early diagnosis, early treatment, and early control are particularly important for improving prognosis. Lupus erythematosus patients should receive standardized treatment in a timely manner, so as not to delay the best treatment time. Although lupus erythematosus is currently incurable, standardized treatment can prolong the life of patients, improve the prognosis of patients, and improve the quality of life.
Strengthen the use of biological agents to provide more treatment options
“Glucocorticoids and hydroxychloroquine are the basic drugs for the treatment of lupus erythematosus.” Director of the Office of the National Clinical Research Center for Skin and Immune Diseases , Li Mengtao, deputy director of the Rheumatology Branch of the Chinese Medical Association and deputy director of the Department of Rheumatology and Immunology of Peking Union Medical College Hospital, introduced that glucocorticoids can quickly control the disease and help patients get through difficulties, but in the process of medication, you must strictly follow the doctor’s advice, and the doctor’s Under the guidance of drug reduction, withdrawal. Although hydrochloroquine is relatively safe, in the process of use, it is still necessary to regularly screen relevant indicators to reduce the incidence of complications.
“With the development of technology, the treatment of lupus erythematosus has also ushered in the era of biological agents.” Li Mengtao introduced that biological agents can achieve more precise inhibition of the patient’s condition and pathogenesis, with relatively high safety. In the course of treatment, it can be combined with basic therapy to better help patients control the disease, reduce the side effects caused by drugs, and improve the survival rate of patients. In recent years, more and more new drugs have been included in medical insurance, which has also eased the financial burden of patients.
Tian Xinping believes that the innovation of biologics is an important progress in the treatment of autoimmune diseases. The previous basic treatment did not have a specific inhibitory effect on the immune system, and the accuracy was relatively poor. By inhibiting or blocking important links in the pathogenesis, biological agents can form precise antagonism or removal of pathogenic links, and provide patients with more treatment options.