Chinanews.com, April 26. According to Taiwan’s “Central News Agency”, Taiwan’s Sun Yat-Sen University said on the 26th that the school’s research and development team cooperated with Kaohsiung Chang Gung Memorial Hospital across institutions to develop a bloodless, painless Chronic kidney disease rapid screening reagents, as long as 15 to 20 minutes to know the results, can avoid the delay of the disease and reduce the risk of infection.
The press release issued by the university stated that this bloodless and painless chronic kidney disease rapid screening reagent was developed by the team of Professor Yang Hongwei of the Institute of Medical Science and Technology of Sun Yat-Sen University and the Department of Pediatric Nephrology of Kaohsiung Chang Gung Memorial Hospital. Physician Tian Youlin cooperated with the team to develop, and it only takes 15 to 20 minutes to know the result.
The cross-school research and development team pointed out that human gut microbes will eat red meat and other foods to produce trimethylamine (TMA), which is converted into trimethylamine oxide (TMAO) by the liver, increasing the risk of cardiovascular disease. risk. In the diagnosis of chronic kidney patients, trimethylamine oxide is considered to be one of the urinary toxins produced by hypertension.
However, the research and development team said that in recent years, a large number of research literature pointed out that a faster and more sensitive detection method is to detect cystin C (CystatinC) in the body to detect early chronic kidney disease, and it is not affected by renal tubules. Reabsorption interference does not differ due to age, gender, body weight, and muscle weight, and is of great significance to the diagnosis and treatment of chronic kidney disease and hypertension.
Yang Hongwei said that this quick screen uses a microneedle patch to extract subcutaneous tissue fluid, and combines with a lateral flow test piece (ie, a pregnancy test stick test piece) for bloodless and painless rapid screening. As long as the microneedle that has been pumped out of tissue fluid is pressed onto the test piece, and then the buffer solution is added, the relative concentration of cystin C can be read in about 15 to 20 minutes, and the patient can be warned early.
Yang Hongwei pointed out that this rapid screening technology has achieved good results in animal experiments, and the research and development results have been published in top international journals. Currently, the cross-school team is planning human trials, and it is expected to be applied to chronic kidney disease in the future. Regular monitoring of the sick at home.