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Omicron BA.2.3 clade discovered in Yantai, Shandong
Introduced at a press conference on epidemic prevention and control held in Yantai, Shandong on April 25, from 0 to 24:00 on April 24, 36 new infections were reported in Yantai, of which 2 were confirmed cases. All cases were common type, and 34 cases were asymptomatic infection.
Image source: Yantai release
Up to now, a total of 16 local cases in 4 districts and cities have been analyzed by gene sequencing, which are the same transmission chain, and the cases are genotyped as Omicron BA.2.3 evolutionary branch. The BA.2.3 evolutionary branch has been detected in the Taichung and Keelung epidemics in Taiwan in February and the fifth wave of epidemics in Hong Kong. (Source: CCTV News)
Shanghai today conducts nucleic acid testing for all personnel in the city’s “three districts”
On April 24, Shanghai added 2,472 local confirmed cases of new coronary pneumonia and 16,983 local asymptomatic infections, and 51 new local deaths. As of 24:00 on April 24, 196 severe patients and 23 critically ill patients had been treated in designated medical institutions.
Source: CCTV News
Since April 22, Shanghai has launched nine major actions to clear the society. On April 26, Shanghai will conduct nucleic acid screening of all personnel in all closure, control and prevention areas. There may be rain in the past two days, and we will further do a good job in on-site organization and environmental disinfection. (Source: The Paper)
The proportion of elderly patients with severe disease is relatively high in Shanghai, with over 60% of those with underlying diseases
The number of critically ill patients has increased, according to a press conference on the prevention and control of the novel coronavirus in Shanghai on April 24.
The critically ill patients admitted in this round have two characteristics: First, the proportion of elderly patients is relatively high. At present, among the patients in designated municipal hospitals, the proportion of people over 70 years old is close to 30%;
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Second, the proportion of patients with underlying diseases is relatively high, more than 60%, of which 40% have more than 3 underlying diseases, mainly including cardiovascular and cerebrovascular diseases, kidney diseases, metabolic diseases diseases, respiratory diseases, neurological diseases and malignant tumors, etc. Vaccination rates in these patients are relatively low. (Source: The Paper)
Tianjin Emergency Center sent 50 120 ambulances to Shanghai for support
On April 25, the Tianjin Emergency Center set up a pre-hospital emergency medical team to assist Shanghai and drove to Shanghai to fully support Shanghai in carrying out pre-hospital medical treatment for the COVID-19 outbreak.
Source: Tianjin Emergency Center
The Tianjin Aid Shanghai Pre-Hospital Emergency Medical Team consists of 108 members, 50 ambulances and 2 support vehicles. The team includes 50 emergency doctors, 52 ambulance drivers, management 6 people. (Source: Tianjin Emergency Center)
The first generic drug of dolutegravir sodium tablets in China to apply for listing
On April 24, the official website of the Center for Drug Evaluation (CDE) of the State Drug Administration showed that Qilu Pharmaceutical’s “dotegravir sodium tablet” marketing application was accepted. This is the first generic drug of dolutegravir sodium tablets to be declared for marketing in China.
Image source: Center for Drug Evaluation, State Drug Administration
Dolutegravir, an HIV integrase inhibitor developed by GlaxoSmithKline, was approved by the China Food and Drug Administration in 2016 for the treatment of human immunodeficiency HIV-infected adults and children 12 years of age and older. (Source: Center for Drug Evaluation, State Drug Administration, GlaxoSmithKline official website)
The State Food and Drug Administration revises the instruction manual of hyacinthine hydrobromide injection
On April 25th, the State Food and Drug Administration issued an announcement on the revision of the instruction manual of Gaconitine Hydrobromide Injection.
Image source: State Food and Drug Administration
In post-marketing surveillance, multiple adverse reactions (incidence unknown) were reported, involving immune system, cardiovascular system, systemic reaction, respiratory system, skin and subcutaneous tissue, gastrointestinal system , nervous system and psychiatric reactions, hepatobiliary system, etc. In addition, there have been case reports of serious adverse reactions of anaphylactic shock. (Source: State Food and Drug Administration)
14 new local confirmed cases in Jiangxi, 116 asymptomatic cases
From 0 to 24:00 on April 24, 14 new local confirmed cases were added in Jiangxi Province (including 5 in Nanchang City and 9 in Shangrao City, all in Wannian County). 2 cases of common type and 12 cases of mild type; 1 new case was cured and discharged (in Nanchang City).
116 new cases of local asymptomatic infections (including 106 cases in Shangrao City, all in Wannian County; 6 cases in Nanchang City; 4 cases in Ji’an City, all of which were imported closed-loop managers from outside the province) found in). (Source: CCTV News)
31 provinces, municipalities and autonomous regions on the 24th2666 new local confirmed cases
From 0 to 24:00 on April 24, 31 provinces (autonomous regions and municipalities) and the Xinjiang Production and Construction Corps reported 2,680 new confirmed cases. Among them, 2666 were local cases (2472 in Shanghai, 79 in Jilin, 26 in Heilongjiang, 14 in Beijing, 14 in Jiangxi, 13 in Zhejiang, 12 in Hunan, 9 in Inner Mongolia, 5 in Henan, 5 in Qinghai, and 4 in Jiangsu. There are 3 cases in Liaoning, 3 cases in Guangdong, 2 cases in Shanxi, 2 cases in Shandong, 1 case in Tianjin, 1 case in Fujian, and 1 case in Sichuan), including 899 cases of asymptomatic infections converted to confirmed cases (846 cases in Shanghai, 39 cases in Jilin, 12 cases in Zhejiang, 1 case in Fujian, and 1 case in Qinghai). 51 new deaths, all local cases, in Shanghai. (Source: National Health Commission)
Issue 821Lilac Early Reading ends here
Planning: Cats
The source of the title map: Zhanku Hailuo