The number of positive infections in Shanghai is still high, repeating nucleic acid testing is very necessary

Shanghai dynamically adjusts the delineation of the “three districts”, and strives to achieve the goal of social clearing in the shortest time. Photo courtesy of the Shanghai Municipal Government Information Office

(Shanghai War Epidemic Record) The number of positive infections in Shanghai is still at a high level. Repeated nucleic acid testing is very necessary

China News Service, Shanghai, April 17th (Reporter Chen Jing) At a press conference on the prevention and control of the new coronary pneumonia epidemic in Shanghai held on the 17th, Wu Jinglei, director of the Shanghai Municipal Health Commission, said that the proportion of positive infections found in risk groups was declining. The number of positive infections found in the past two days is still high, but relatively stable.

On the 16th, Shanghai added 3,238 local confirmed cases of new coronary pneumonia and 21,582 local asymptomatic infections. 307 confirmed cases and 415 local asymptomatic infections were found in nucleic acid screening of relevant risk groups. Wu Jinglei explained that among the 3,238 local confirmed cases, 1,754 were found in closed-loop isolation and control, 307 were found in nucleic acid screening of relevant risk groups, and 1,177 were asymptomatic infected persons who were transferred to confirmed cases, and the actual new confirmed cases were 2061 cases.

He said that Shanghai will focus on key points, zoning and grading, and implement nucleic acid screening as the main method, supplemented by antigen screening, and implement full-staff testing and screening for personnel in the closed control area, control area, and prevention area. , and will dynamically adjust the delineation of the “three zones” based on the results of periodic screening, and strive to achieve the goal of social clearance in the shortest possible time.

Currently, 16 severe cases are being treated in hospitals. Wu Jinglei said that among the 16 severe cases, the youngest was 33 years old, and the others were elderly people over 70 years old. Of the 16 people, only one was vaccinated throughout the course, and none of the others had been vaccinated against the new coronavirus. Wu Jinglei said that the 33-year-old patient suffered from a severe autoimmune disease, and his immune function declined significantly; at the same time, he had poor kidney function and required hemodialysis maintenance. At present, after active antiviral symptomatic treatment, combined with traditional Chinese medicine treatment, the patient’s lung imaging has improved, and related underlying diseases are still being actively treated. Other elderly critically ill patients have serious underlying diseases.

He said that in accordance with the principle of “one person, one plan”, the designated hospitals have increased the treatment force and carried out multidisciplinary expert consultations. In view of the characteristics of severe patients with serious underlying diseases, while actively treating new coronary pneumonia, Ventilator-assisted ventilation, extracorporeal model lung (ECMO), antiviral, anti-infective, symptomatic nutritional support and other treatments were given. Wu Jinglei said that the designated hospitals pay special attention to the treatment of these critically ill patients with traditional Chinese medicine, which complements the advantages of modern medicine and western medicine. The medical staff also paid special attention to observe the changes in the condition of critically ill patients and made every effort to treat them.

Nucleic acid detection is an important means of prevention and control of new coronavirus infection. At present, Shanghai is still carrying out high-frequency repeated nucleic acid testing? Gao Chunfang, director of the Testing and Experiment Center of Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, said that repeated testing is necessary to detect positive infections. Through population nucleic acid testing, cases, especially asymptomatic infections, can be detected as soon as possible, risk areas and key groups can be identified and locked, and targeted control measures can be taken in a timely manner to stop the spread of the epidemic.

Gao Chunfang said that in terms of the occurrence and development of clinical diseases, any pathogen infection has a certain incubation period, and the new crown is no exception, and there are certain individual differences in the length of the incubation period. From the perspective of detection technology, there is the concept of detection window period. After virus infection, there is a growth and replication process in the body. In the early stage of infection, the viral load is too low, below the lower limit of detection, and positive can not be found. This time period is the detection window period. The expert said that the incubation period of infection + the detection window period makes it impossible to detect positive results in the early stage of infection. Repeated testing can increase the probability of positive detection and timely detection of positive results.

It is reported that, due to the sampling of respiratory pathogens mainly in the form of throat swabs, nasal swabs, and nasal + pharyngeal swabs, there are inevitably certain sampling differences in the sampling process. Such differences include sampling site, depth, and amount of collected secretions. Therefore, repeated sampling and testing can make up for the possible false negative effects caused by sampling errors.

Gao Chunfang said, in addition, for those who have been infected, during the development of the disease, repeated detection and monitoring of load changes provide a good indicator for predicting the treatment effect and recovery status of infected patients. Repeated testing is a routine practice for clinical pathogen confirmation. For example, for other infectious diseases such as urinary tract infection and blood tract infection, multiple culture (more than three times) monitoring is usually required to confirm positive pathogens and achieve precise treatment. (End) [Editor: Huang Yuhan]