Long-term risk of atrial fibrillation and stroke after coronary artery bypass grafting: 10-year results from the ART study

Postoperative atrial fibrillation (pAF) is a common complication after coronary artery bypass grafting. Whether pAF is associated with an increased risk of cerebrovascular accident (CVA) is unclear.

ART (Arterial Revascularization Trial) enrolled 3102 cases, except no surgery (n=25), history of atrial fibrillation (n=45), no After reporting pAF (n=9), a total of 3023 patients were included in the study, of which 734 (24.3%) developed pAF and the remaining 2289 patients maintained sinus rhythm.

At 10-year follow-up, the cumulative incidence of CVA was 6.3% (4.6%–8.1%) and 3.7% in the pAF and sinus rhythm groups, respectively (2.9%–4.5%). At 10-year follow-up, pAF was an independent predictor of CVA.

CVA risk was significantly increased in pAF patients after coronary artery bypass grafting.

Baseline characteristics are shown in the table below,

Related to 10-year CVA event The clinical factors are shown in the table below,

CVA event risk comparison is shown in the figure below,

with The clinical factors associated with cardiac death at 10 years are shown in the table below,

Cardiac and all-cause mortality comparisons are shown below,

The comparison of different CHA2DS2-Vasc scores is shown in the figure below,

Circulation. 2020;142 : 1320–1329.