Case Details Guide 1
Esketamine
Esketamine is an NMDA receptor antagonist with analgesic, sedative, amnestic effects, and mild respiratory depression; blocking injury Central sensitization caused by sexual stimulation; Enhanced uterine contractions, which are beneficial to postpartum uterine involution; Sympathomimetic effects, offsetting the depressive effects of sevoflurane on the nervous and cardiovascular systems during general anesthesia; Reduced opioid consumption for cesarean section ( 30%); esketamine has a lower incidence of psychiatric adverse events than ketamine, and the recovery rate is faster; there is no significant effect on the fetus at commonly used doses.
Introduction 2
Case Summary and Experience
The use of a small amount of esketamine (0.05-0.1mg/kg) significantly relieved the cesarean section. Compared with the previous low-dose sufentanil in the pot to relieve the discomfort of pulling on the internal organs of the mother, not only the effect is accurate, but also there is no risk of respiratory depression caused by opioids entering the mother’s body quickly. Moreover, the sedative effect of esketamine has a significant effect on relieving maternal tension and discomfort, and significantly improves maternal satisfaction with anesthesia surgery. Esketamine is suitable for induction and maintenance of anesthesia, and can also be used for postoperative analgesia. There is no obvious restriction on the type of surgery. However, it should be used with caution if the patient has obvious hypertension and tonic contractions of the puerperium.
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