Among many liver diseases, hepatitis B has always been the most aggressive one. Because of the latent, harmful and strong replication of hepatitis B virus, it is difficult to pass medical treatment. Means quick and thorough removal. For now, the best way to treat hepatitis B is still prevention, and the effect of prevention and treatment of hepatitis B is achieved by injecting vaccines in the early years.
But because of this, many patients who have been infected by hepatitis B virus and suffer from hepatitis B cannot receive effective and thorough treatment. . Modern medicine is also making continuous efforts to completely overcome the problem of hepatitis B treatment through the research of new drugs. And my country’s research in this area is fruitful.
China’s new hepatitis B drug CB06 has completed phase 1 study in the United States
IncludingCB06, a novel therapeutic agent for hepatitis B virus under development, which has completed Phase 1 trials in US laboratories, And completed the drug administration process for the subjects in the clinic.
According to researchers, CB06 is different from conventional hepatitis B therapeutics in that it is produced by single-chain The method of RNA gene identification, to achieve the purpose of searching for hepatitis B virus and completely eliminating the hepatitis B virus.
In other words, if this domestic new hepatitis B drug CB06 can be successfully developed, it will be able to further improve the clearance efficiency of hepatitis B virus. And CB06 can induce cytokines to activate the immune system, and further improve the healing effect of hepatitis B.
Not only that, according to further drug introduction, most patients with hepatitis B virus infection will also be accompanied by clinical symptoms such as chronic hepatitis, CB06 has good liver targeting and can also play a very good role in the remission therapy of chronic hepatitis.
In conclusion, this new domestic hepatitis B drug under development is worthy of the expectation of patients who are in the difficult and long course of hepatitis B treatment. The research and development of new drugs also seems to point out a new direction for the treatment of hepatitis B.
What is the future direction of hepatitis B treatment?
At present, the treatment of hepatitis B still focuses on eliminating the virus and nourishing the liver. Through long-term treatment, the purpose of clinical cure is achieved.
The reason why hepatitis B is difficult to completely eradicate is because the hepatitis B virus will produce a virus called during the replication process. The accessory product of cccDNA, and DNA does not belong to the category of virus, and there is no way to completely remove it by drugs. Hepatitis B virus replicates with the “template” of cccDNA, and it will be exponentially more difficult to completely cure it.
Therefore, the future direction of hepatitis B treatment may be based on DNA gene level treatment. By correcting the sequence of cccDNA, the process of cyclic replication of hepatitis B virus is disrupted, so as to achieve the purpose of thorough treatment. CB06 adopts a similar method, through the research and development of synthetase, to achieve the purpose of conquering hepatitis B at the DNA level.
In other words, the future treatment of hepatitis B has already found a clear direction. With the development of CB06 and other similar drugs, it is believed that in the near future, Hepatitis B can really be a completely curable disease.
But then again, if hepatitis B patients want to wait for that day, they must focus on the present and actively cooperate with the existing hepatitis B treatment process. Scientific nursing can prevent further deterioration of symptoms. In the process of recuperating hepatitis B, some traps must be learned to avoid in order to further ensure the effectiveness of hepatitis B treatment.
Actively cooperate with hepatitis B treatment and avoid 3 “misunderstandings”
①Antiviral drugs, the more you eat, the better
Take antiviral drugs , is one of the main steps in the treatment of hepatitis B patients, through sufficient drug intake, can inhibitVirus, the effect of restoring liver function.
However, although the effect of antiviral drugs is limited, it is not that the more you eat, the better. On the one hand, if takes too much medicine blindly, it will lead to drug resistance of the virus and affect subsequent treatment.
On the other hand, antiviral drugs are inherently toxic, and taking too much will cause the liver to Metabolic burden. Therefore, the medication must be strictly followed by the doctor’s advice, especially for patients with hepatitis B accompanied by severe liver disease, it is necessary to strictly limit the medication according to the course of treatment.
②Antiviral treatment will prevent infection
After antiviral treatment, it does not mean that there is no risk of hepatitis B infection in the body.
In contrast, even with antiviral therapy,dormant or latent hepatitis B remains in the body Virus. During the follow-up recuperation, in order to avoid infecting family members, personal daily necessities should still be used separately, and corresponding measures should be taken during sex. Protective measures.
③No examination after hepatitis B treatment
After the hepatitis B antiviral treatment, review is also an important part. The reason why hepatitis B is difficult to treat is inseparable from its stubbornness and recurrence. Even after treatment, regular re-examinations are required, and improvement of nursing measures according to the doctor’s advice is the most correct choice.
In general, patients who have just finished antiviral therapy, recommended to visit the hospital every 3 months Check again, if there are significant abnormal symptoms such as liver pain, fatigue, loss of appetite, etc., Please also go to the hospital in time for corresponding examination and treatment.
All in all, the future development of hepatitis B treatment and related special drugs is worth looking forward to, but for now, hepatitis B patients still need to do their daily We need to work on the treatment of the disease and actively cooperate with antiviral treatment to better stabilize the disease. Waiting for the arrival of the day when hepatitis B is completely cured, we can rekindle the hope of health.
References:
[1]Zhang Ruijun, Hu Linzhu, Wu Jiaxin , et al. Effects of TLR3 on Th1/Th2 cytokines in cord blood mononuclear cells of infants with no weak response to hepatitis B vaccine [J]. Chinese Journal of Disease Control, 2020, 24(6):6.
[2]Chen Jiankang. Several misunderstandings of hepatitis B transmission[J]. Health Must Read 2020, No. 26, 184 pages, 2020.