Top 3 Heaven Group

Wang Renzhong

Shanghai Anda Hospital Attending Physician

What are Can medications affect test results?

Doctors often ask patients to do tests to help Disease diagnosis, but if the patient is taking certain medicines that may affect the test results without telling the doctor, it can often lead to misdiagnosis or missed diagnosis.

Common Medications That Can Cause Abnormal Test Results

Antibacterials

For example, penicillins and sulfonamides increase blood uric acid levels; kanamycin and neomycin lower blood cholesterol levels.

hormones

Glucocorticoids (such as prednisone, dexamethasone, etc.) Can increase blood sugar; mineralocorticoids (such as deoxycorticosterone) can reduce serum potassium; estrogens (such as estradiol, etc.) can reduce blood platelets, red blood cells, and increase transaminases.

Diuretics span>

Among them, potassium-sparing diuretics such as furosemide, hydrochlorothiazide, etc. , will promote the renal excretion of potassium, long-term use may cause hypokalemia and hypochloremia.

cancer drugs< /span>

Most anticancer drugs such as cytarabine , cyclophosphamide, vincristine, etc.) will affect the human hematopoietic system, reduce red blood cells, white blood cells, platelets and hemoglobin in the blood, and also damage liver function and increase transaminase.

NSAIDs and CNS Analgesics

such as ibuprofen , indomethacin, domeridine, morphine and codeine, etc., can make the sphincter of Oddi in the common bile duct spasm, and increase the amylase in the blood and urine.

Hypoglycemics

< span>Among them, tolbutamide and chlorpropamide can cause leukocyte, granulocyte and thrombocytopenia. Voglibose can cause hyperkalemia, increase blood amylase, and lower high-density lipoprotein cholesterol.

Anticagulants< /span>

Among them, heparin can prolong bleeding and coagulation time, and can also Reduce blood leukocytes, increase serum total triiodothyronine (T3) and thyroxine (T4) concentrations, heparin also promotes the release of tissue lipoproteinases and reduces blood triglycerides.

vitamins< /span>

High-dose vitamin C can make urine and fecal occult blood test False negative and elevated uric acid.

Vitamin B2 causes can bind to bilirubin,Lower urinary bilirubin.

Vitamin A and vitamin D can raise blood cholesterol.

Vitamin A can speed up ESR, 24 Do not take vitamin A for hours.

Antiarrhythmics

Amiodarone inhibits the conversion of T4 to T3, resulting in Blood T4 increased and T3 decreased.

Anti-epileptic drugs< /span>

Among them, phenytoin sodium can inhibit the absorption of folic acid and cause megaloblastic Red blood cell anemia. It also reduces white blood cells and platelets.

How to avoid drugs that affect test results from affecting test results

The correctness of the test results plays an important role in the diagnosis of the disease. Therefore, both doctors and patients should pay enough attention to this.

In order to avoid unnecessary misdiagnosis and missed diagnosis, span>

1

As a doctor, when prescribing a test order, you should learn about the specific conditions of each drug that can affect the test result, and instruct the patient to stop or choose other drugs before the test, or wait until the drug’s time limit expires. assay.

2

As a patient, if you go to the hospital for treatment, you should inform your doctor in detail about all the medicines you are currently taking; if you participate in a planned physical examination, you can ask your doctor or pharmacist before the physical examination whether the medicines you take will affect the test The results have an impact on whether to adjust the medication.

Only in this way can the influence of drugs on test results be minimized, and correct diagnosis and treatment guidance can be obtained.

|First article: Journal of Family Medicine