Birth, old age, sickness and death are the laws of nature. All creatures face aging, and so do human beings. Aging is something that no one is willing to face, and will delay aging by taking health care products, doing beauty treatments or taking medicines. Some time ago, the news of blood transfusion reversing aging attracted so many people’s attention that a clinical trial of blood transfusion anti-aging was carried out. Can young serum really reverse cellular aging?

Young blood or the secret code of immortality

A report was published in the journal Nature Aging, which was published by a research team at the University of Pittsburgh. The study showed that in terms of muscle aging, extracellular vesicles carrying the longevity protein Klotho in the blood mediated, so the output of young blood can reverse aging.

The research team used the serum of young mice for experiments, cultivated muscle stem cells and injected them into old mice to study cells Age-related changes in outer vesicles cause Klothol depletion in senescent stem cells, which were found to improve myogenic potential in aged mice.

Because young serum can change the mitochondrial structure of cells and increase the oxygen consumption of aging muscle stem cells, thereby increasing cardiolipin levels. The role of its central phospholipids is to maintain mitochondrial integrity and regulate oxidative phosphorylation. The mechanisms by which molecules in serum affect mitochondria and recipient cells are generally related to extracellular vesicle trafficking.

The research team performed live cell respiration and immunofluorescence assays on the serum of young and old mice depleted of extracellular vesicles and found that The previous changes were all gone, and the youthful changes were restored after the isolated extracellular vesicles were replenished to the serum. After bone injury in aged mice, the research team injected serum from young mice through the tail vein, which increased the dependence of extracellular vesicles, and enhanced skeletal muscle regeneration and functional recovery after 11 days.

Young blood can also be used for Alzheimer’s treatment

Stanford University research team found that young plasma not only improved the brain rejuvenation of old mice, but also improved physical and cognitive performance. Then began clinical trials on humans, processing blood donated from 18 to 25 years old to remove most of the proteins and other molecules and make it into plasma.

18 patients with mild to moderate dementia were recruited for the trial, and the plasma was injected once a week for 4 weeks. It was concluded that there were no adverse effects and no significant improvement in cognition after plasma transfusion, but there was a significant improvement in shopping and cooking abilities.

How to keep yourself young and delay aging in daily life?

1. Swimming

Adhering to swimming not only exercises the flexibility of the limbs, but also improves the cardiopulmonary function, maintains a youthful state of the heart and lungs, and can also help control weight and shape, and delay aging.

2, jogging

Jogging is a good aerobic exercise, which can improve cardiopulmonary function, improve the ability of blood to carry oxygen, make all tissues and organs get enough oxygen and blood supply, and effectively delay aging.

3. Practice yoga

Persistent practice of yoga can stretch the muscles and bones, improve the flexibility of the body, and can also promote the blood circulation of the whole body.make people look younger.

Reminders

Although aging cannot be reversed, there are many ways to delay the onset of aging. Usually, you should pay attention to nutritional balance and diversification, do a good job in the combination of meat and vegetables, and ensure a balanced intake of various nutrients; maintain a positive and optimistic attitude, and eliminate negative emotions in time; adhere to the combination of aerobic exercise and strength training, and at the same time have enough sleep, Can maintain youthful state and delay aging.

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