Have you ever thought about this question, how much effort and exploration it takes to create a new drug and then go on sale? From discovery to recognition to confirmation, what happened in this process?
Click the video below to see what the experts have to say
Pharmaceutical research for new drugs is an exploratory research process, starting from the unknown and conducting drug screening and discovery research based on clinical needs. It mainly includes the following three steps:
Step 1: Complete the confirmation of the research target, and screen out the active compounds from millions of candidate compounds.
Step 2: Preclinical studies in animals focused on assessing the safety of the drug and providing data support for first-in-human trials.
The third step: Phase I-IV human clinical trials.
Among them, the Phase I clinical trial is a preliminary evaluation of clinical pharmacology and human safety. The test subjects are generally healthy volunteers. The subjects of the Phase I clinical trial of anti-tumor drugs are Not healthy people, but tumor patients; Phase II clinical trials are the preliminary evaluation stage of drug treatment effects, evaluating the therapeutic effects and safety of drugs on patients with target indications; Phase III clinical trials are the confirmation stage of drug treatment effects, and further Verify the therapeutic effect and safety of the drug on patients with the target indications, evaluate the relationship between benefits and risks, and ultimately provide a sufficient basis for drug registration applications; Phase IV clinical trials are the monitoring and evaluation of drugs after they are marketed.
Thanks to the above pharmacy experts for their generous contributions to this video
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