Expert in this article: Qin Wei, Ph.D., Pharmacist in charge of the Department of Pharmacy, China-Japan Friendship Hospital
I believe that many people are familiar with ibuprofen. Especially female friends.
Stomach pain, take ibuprofen…
Head migraine, take an ibuprofen…< /span>
Fever, ibuprofen, arrange…
Even many people take ibuprofen no matter where the pain is, then Is ibuprofen really a panacea? What are the side effects of eating too much?
Let’s learn together today.
Ibuprofen is a panacea?
Ibuprofen is a non-steroidal anti-inflammatory drug with analgesic, antipyretic and anti-inflammatory properties. It reduces prostaglandin synthesis by inhibiting cyclooxygenase, thereby reducing tissue congestion and swelling caused by prostaglandins, and reducing peripheral nerve pain sensitivity. In addition, it can also play an antipyretic (commonly known as “fever reduction”) effect by acting on the hypothalamus thermoregulatory center.
Ibuprofen can relieve many types of pain, including Headache, arthralgia, migraine, toothache, muscle pain, neuralgia, dysmenorrhea, postoperative pain, low back pain, post-exercise injury pain; pain caused by strain, tenosynovitis, bursitis; rheumatoid arthritis, osteoarthritis, Other non-rheumatoid arthritis and acute gout.
The efficacy of ibuprofen covers almost all kinds of pain that will be encountered in daily life, but please Note that when you encounter certain pains, if takes painkillers blindly, it may delay the disease.
The most dangerous of these is pain from heart disease, which can cause Cardiogenic toothache, back pain, shoulder pain, chest pain. Seek medical attention as soon as possible when it occurs. Do not take painkillers by yourself, which will delay the best treatment time.
Who should not take ibuprofen?
1. Pregnant women are prohibited
ibuprofen may pass through the placenta, Causes damage to the fetus. Use over 20 weeks can cause fetal kidney damage and increase the risk of amniotic fluid insufficiency.
2. Lactating women
Ibuprofen can enter breast milk, lactating women If taking medication, stop breastfeeding.
3, women who are trying to conceive
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It can delay or prevent ovulation and cause reversible infertility. Therefore, women planning to become pregnant should use this drug with caution. Consider stopping the drug.
4. Patients with peptic ulcer or gastrointestinal bleeding
ibuprofen can Inhibits the activity of cyclooxygenase 1, which plays a protective role in the gastrointestinal mucosa, aggravating ulcers or bleeding.
5. Patients with heart disease
Oral high-dose (≥2400mg/day) cloth Profen is associated with an increased risk of heart attack and stroke, and the risk increases with dose and duration of use.
6. Patients with liver disease and kidney disease
Because ibuprofen passes through the liver Metabolized and excreted by the kidneys, taking ibuprofen may exacerbate the condition in such patients.
What are the side effects of taking too much ibuprofen?
The following side effects may occur with normal use of ibuprofen: nausea, vomiting, heartburn, mild indigestion, headache, dizziness, ringing in the ears, vision Blurredness, nervousness, lethargy, lower extremity edema, or sudden weight gain.
If overdose or taken for a long time, it may cause serious side effects, including severe gastrointestinal reactions (such as bleeding, ulcers, perforation, Abdominal pain, bloating, etc.), severe cardiovascular thrombotic events (may be manifested as chest pain, shortness of breath, weakness, slurred speech, etc.), severe skin reactions (such as exfoliative dermatitis, Steven’s syndrome).
If the above symptoms occur while taking the medicine, or if a rash or other allergic reaction occurs during the first dose of , please stop taking the medicine and see a doctor.
Precautions for taking ibuprofen?
BetterDo not use ibuprofen for a long time or in large quantities, please do not exceed 5 days for pain relief, and do not exceed 5 days for antipyretic 3 days.
Drinking alcohol while taking medication may increase the risk of gastrointestinal bleeding and serious cardiovascular side effects, Please avoid alcohol or alcoholic beverages.
Ibuprofen may inhibit your blood clotting, may be easier after taking it Bleeding, please use a soft toothbrush and electric shaver.
Please do not take other medicines containing antipyretic and analgesic ingredients at the same time,< /span>Be especially carefulsome combination cold medicines may contain NSAIDs.
Clothes Profen may induce or aggravate high blood pressure. It is recommended that you monitor your blood pressure closely.If you are concerned about overdose, you can monitor the blood concentration of ibuprofen in the hospital.
Source: Popular Science China