內容目錄
Cover reporter Zhou Jiayi Photo courtesy of the interviewee
The total number of adults with diabetes in China ranks first in the world, reaching 140 million1,3, and the prevalence rate is also rising, reaching 12.8%. Among them, type 2 diabetes accounted for the majority, of which only 16.5% of the patients achieved blood sugar control. On March 5th, at the media conference on “High Standards, Benefit Control, and Benefit New Era”, Professor Mu Yiming, director of the Endocrinology Department of the First Medical Center of the PLA General Hospital, pointed out that in order to achieve the ideal blood sugar control goal for diabetic patients, in addition to lowering blood sugar levels In addition to sugar, it is also necessary to pay attention to the stability of blood sugar, the safety of hypoglycemia, and to achieve “high-quality compliance.”
100 years ago, the discovery of insulin turned diabetes from an incurable disease into a manageable disease. In the past 100 years, hypoglycemic drugs have experienced rapid development, but the blood sugar control of patients with diabetes still faces many challenges. From the perspective of the patients themselves, factors such as poor pancreatic islet secretion capacity, high blood sugar fragility, and complications with the prolongation of the disease course may all lead to Increase the difficulty of treatment; from the perspective of the treatment plan, it is necessary to effectively reduce blood sugar while taking into account safety issues such as low risk of hypoglycemia.
For diabetics, frequent and excessive blood sugar fluctuations are even more harmful than persistent Continuous damage to vascular endothelial cells throughout the body increases the risk of diabetes complications, which may lead to serious consequences such as blindness, renal failure, heart attack, stroke, and lower limb amputation, which not only affects the quality of life of patients, but also increases the economic burden on families and society. .
Therefore, high blood sugar control is the first priority of blood sugar management in diabetic patients. Controlling blood sugar to the target as soon as possible will help reduce or delay the occurrence of diabetes complications. Prof. Yiming Mu emphasized that for patients with poor control of oral hypoglycemic drugs and basal insulin in actual treatment, blood sugar management needs to achieve real “high-quality standards” – blood sugar control standards, stable blood sugar control, and safe blood sugar control (hypoglycemia). low risk and avoidance of weight gain side effects). The world’s first basal insulin GLP-1RA injection, launched recently, can be combined with other oral hypoglycemic drugs on the basis of diet and exercise to improve blood sugar control and help Chinese patients with type 2 diabetes achieve high-quality blood sugar compliance.
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