Zhang Wenhong on Unexplained Hepatitis in Children: There is an Imported Risk, Prepare for This Early

“Huashan Infection” WeChat public account published a document on April 29 to introduce the development and possible causes of hepatitis in children of unknown cause in the UK and other places. The article pointed out that there is an imported risk of unexplained childhood hepatitis, and my country should prepare for it early.

Zhang Wenhong, director of the National Center for Infectious Diseases Medicine and director of the Department of Infectious Diseases of Huashan Hospital Affiliated to Fudan University, commented in the article that unexplained hepatitis cases occur every year, often referring to known hepatitis viruses or known Caused liver damage, which is not uncommon in children. However, the unexplained hepatitis that WHO is concerned about has the characteristics of clustered disease, and the incidence rate is higher than in previous years. In this case, it is reasonable to consider the risk of infectious diseases.

Zhang Wenhong said that there is a certain correlation with adenovirus infection. But adenovirus infection is a very common phenomenon that can cause pneumonia or diarrhea. Why are there so many cases of severe hepatitis this year, and only in children? At present, it is speculated that it is a long-term isolation of the new crown. Children have not been exposed to this virus for a long time, and sudden contact will cause relatively serious immune damage. This speculation is consistent with the phenomenon that emerging infectious diseases tend to be heavier in the early stage of disease outbreaks. of.

Zhang Wenhong believes that if it is caused by the long-term isolation of the new crown, rather than a new virus that has not been discovered before, the follow-up effect of this unexplained hepatitis will gradually decline, but we Vigilance against unknown pathogens is also required, even if the probability of a pandemic of this emerging infectious disease is not high. In addition, the current definition of a confirmed case is constantly being updated as awareness grows.